Results 181 to 190 of about 529,334 (314)

The Liver Clock Tunes Transcriptional Rhythms in Skeletal Muscle to Regulate Mitochondrial Function. [PDF]

open access: yesJ Biol Rhythms
Sica V   +9 more
europepmc   +1 more source

Ninjin’yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression

open access: green, 2020
Atsushi Miyamoto   +10 more
openalex   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

open access: yesAdvanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang   +12 more
wiley   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

Critical role of mitochondrial aconitase in skeletal muscle maturation. [PDF]

open access: yesSci Rep
Fukawa T   +14 more
europepmc   +1 more source

Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots

open access: yesAdvanced Science, EarlyView.
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro   +11 more
wiley   +1 more source

Intracellular amyloidosis in peripheral nerve and skeletal muscle. [PDF]

open access: yesJ Neuropathol Exp Neurol
Grafham GK   +6 more
europepmc   +1 more source

AMP‐activated protein kinase response to contractions and treatment with the AMPK activator AICAR in young adult and old skeletal muscle

open access: green, 2009
David M. Thomson   +7 more
openalex   +2 more sources

Inositol Phospholipid 3‐Kinase is Activated by Cellular Stress but is not Required for the Stress‐Induced Activation of Glucose Transport in L6 Rat Skeletal Muscle Cells [PDF]

open access: bronze, 1997
H E McDowell   +6 more
openalex   +1 more source

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