Results 241 to 250 of about 1,531,774 (311)

A peripheral perspective on brain health: vascular and skeletal muscle contributions. [PDF]

Am J Physiol Heart Circ Physiol
Keller JL, Pennartz KJ, Sprick JD, Hein EJ, Irving BA, Vann CG, Butlig ER, Al-Masri S, Nelson AR.   +8 more
europepmc   +1 more source

Loss of Intestinal MSTN Promotes GLP‐1 Secretion Through SGLT1 Palmitoylation

Advanced Science, EarlyView.
Intestinal MSTN deficiency enhances glucose‐stimulated GLP‐1 secretion and glucose tolerance in high‐fat diet‐fed mice. Mechanistically, loss of MSTN promotes YY1‐associated ZDHHC20 expression, increasing SGLT1 S‐palmitoylation at Cys301 and its plasma membrane localization in L cells.
Sheng‐Zhong Han, Shuang‐Yan Chang, Zhaobo Luo, Ke Sun, Biaohu Quan, Yanqiu Lv, Zhouyan Li, Xinyue Liu, Sitong Lv, Meifu Xuan, Xiaoyufan Xu, Xue Fang, Hang Chang, Rihuan Zhang, Xi‐Jun Yin, Lin‐Hu Quan, Jin‐Dan Kang   +16 more
wiley   +1 more source

Oxytocin as a regulator of skeletal muscle plasticity and metabolic function. [PDF]

Front Endocrinol (Lausanne)
da Cruz-Filho J, Lustrino D.
europepmc   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

Advanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye, Miaoru Han, Siqiao Tang, Zongxiang Zhang, Haichen Shen, Bingzhen Sun, Yan Zhang, Xiaodong Chu, Lijuan Deng, Chaoyang Zheng, Qingchun Huang, Kun Bao, Ronghua Zhang, Yong Wang, Fengwei Zhang, Xiaoli Chu   +15 more
wiley   +1 more source

Microbial-derived exerkines outperform creatine monohydrate in enhancing skeletal muscle adaptation to exercise in mice. [PDF]

Am J Physiol Cell Physiol
Burke BI, Daredia J, El-Amouri SS, Range LC, Pearson JR, Valentino TR, McCarthy JJ, Wen Y, Ismaeel A.   +8 more
europepmc   +1 more source

Appendicular Skeletal Muscle Mass and Sarcopenia as Prognostic Markers in Amyotrophic Lateral Sclerosis. [PDF]

J Cachexia Sarcopenia Muscle
Zarco-Martín MT, Andreo-López MC, Yagui-Beltrán MS, Fernández-Soto ML.   +3 more
europepmc   +1 more source

Lycopene Increases Skeletal Muscle Mass by Promoting Myoblast Differentiation. [PDF]

Food Sci Nutr
Wen W, Ding D, Pu J, Zhang Y, Luo Y, Du J, Mou D.   +6 more
europepmc   +1 more source

Activation of ATP Consumption Is Necessary to Stimulate Glycogenolysis in Skeletal Muscle. [PDF]

Int J Mol Sci
Martinov MV, Sudarkina SI, Ataullakhanov FI, Vitvitsky VM.   +3 more
europepmc   +1 more source