Results 271 to 280 of about 965,762 (355)
Overnutrition exacerbates insulin resistance (IR) and is linked to excessive mitochondrial protein acetylation. However, it remains unclear whether and how mitochondrial protein acetylation influences IR. GCN5L1‐dependent downregulation of GRP75 acetylation at K567/612 consequently enhances ER‐mitochondrial calcium flux and induces ER stress.
Danni Wang +13 more
wiley +1 more source
Whole-Body Skeletal Muscle MRI Patterns in Female Dystrophinopathy Carriers. [PDF]
Vigliano AP +10 more
europepmc +1 more source
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang +5 more
wiley +1 more source
Editorial: Exploring genetic and environmental factors in skeletal muscle development. [PDF]
Luo J, Du J.
europepmc +1 more source
Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration
Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang +16 more
wiley +1 more source
Stromal cells unifying the pathology of acute and chronic skeletal muscle injury - clue for novel biomaterials. [PDF]
Liu X.
europepmc +1 more source
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang +19 more
wiley +1 more source

