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Regeneration of skeletal muscle

Cell and Tissue Research, 2011
Skeletal muscle has a robust capacity for regeneration following injury. However, few if any effective therapeutic options for volumetric muscle loss are available. Autologous muscle grafts or muscle transposition represent possible salvage procedures for the restoration of mass and function but these approaches have limited success and are plagued by ...
Stephen F. Badylak, Neill J. Turner
openaire   +2 more sources

Skeletal muscle channelopathies

Journal of Neurology, 2002
Ion channelopathies have common clinical features, recurrent patterns of mutations, and almost predictable mechanisms of pathogenesis. In skeletal muscle, disorders are associated with mutations in voltage-gated Na(+), K(+), Ca(2+), and Cl(-) channels leading to hypoexcitability, causing periodic paralysis and to hyperexcitabilty, resulting in myotonia
Holger Lerche   +2 more
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Hemangioma of skeletal muscle

Archives of Orthopaedic and Trauma Surgery, 2000
Intramuscular hemangiomas are rare benign tumors, making up 0.8% of all hemangiomas. They are of interest to the surgeon because their location may present considerable therapeutic challenge since radiographic work-up of the soft- tissue mass by magnetic resonance imaging (MRI) may be suspicious for malignancy.
A. Wild, Peter Raab, Ruediger Krauspe
openaire   +3 more sources

Patterning of skeletal muscle

Current Opinion in Neurobiology, 2002
Recent studies challenge the view that signals provided by motor neurons are required to activate subsynaptic nuclei and induce postsynaptic specializations in developing skeletal muscle. New findings show that acetylcholine receptor genes are expressed and that acetylcholine receptor clusters form preferentially in the prospective synaptic region of ...
Arber, S., Burden, S. J., Harris, A. J.
openaire   +3 more sources

Skeletal muscle regeneration

Muscle & Nerve, 1981
AbstractThe historical and current research literature is reviewed with special attention to the role of the satellite cell in the reconstitution of skeletal muscle following damage. Implications for the clinical management of trauma patients are stressed in the light of this new knowledge.
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Effects in Skeletal Muscle

2005
The first biological action of amylin to be described was the inhibition of insulin-stimulated incorporation of radiolabeled glucose into glycogen in the isolated soleus muscle of the rat. This antagonism of insulin action in muscle was non-competitive, occurring with equal potency and efficacy at all insulin concentrations. Amylin inhibited activation
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Diseases of the skeletal muscle

2018
After the advances created by the use of cryostat sections and histochemistry 60 years ago, muscle histopathology is now living a real renaissance. In the field of genetic neuromuscular disorders, muscle biopsy analysis is fundamental to address questions about pathogenicity and protein expression when new genes are discovered through next-generation ...
Edoardo Malfatti, Norma B. Romero
openaire   +3 more sources

Glucocorticoids and Skeletal Muscle

2015
Glucocorticoids are known to regulate protein metabolism in skeletal muscle, producing a catabolic effect that is opposite that of insulin. In many catabolic diseases, such as sepsis, starvation, and cancer cachexia, endogenous glucocorticoids are elevated contributing to the loss of muscle mass and function.
Sue C. Bodine, J. David Furlow
openaire   +3 more sources

Skeletal muscle calcergy

The Journal of Pathology, 1982
AbstractThe subcutaneous injection of mast cell degranulators in the mouse is followed by calcification of fibres of the Panniculus Carnosus muscle. This reaction is seen in damaged fibres adjacent to a central zone of complete necrosis. Calcification of muscle fibres is also seen after the injection of KMnO4 but this uniformly affects the fibres at ...
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Skeletal Muscle

2005
Ana M, Fernandez, Derek, LeRoith
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