Results 51 to 60 of about 14,964 (289)

Extracting 3D parametric curves from 2D images of Helical objects [PDF]

open access: yes, 2017
Helical objects occur in medicine, biology, cosmetics, nanotechnology, and engineering. Extracting a 3D parametric curve from a 2D image of a helical object has many practical applications, in particular being able to extract metrics such as tortuosity ...
Jackson, Philip T.G.   +3 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Testing Foundations of Biological Scaling Theory Using Automated Measurements of Vascular Networks

open access: yes, 2015
Scientists have long sought to understand how vascular networks supply blood and oxygen to cells throughout the body. Recent work focuses on principles that constrain how vessel size changes through branching generations from the aorta to capillaries and
Ennis, Daniel B   +2 more
core   +3 more sources

Automated Video Analysis of Animal Movements Using Gabor Orientation Filters [PDF]

open access: yes, 2010
To quantify locomotory behavior, tools for determining the location and shape of an animal’s body are a first requirement. Video recording is a convenient technology to store raw movement data, but extracting body coordinates from video recordings is a ...
Kristan, Wiliam B., Jr.   +1 more
core   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Performance Assessment of Two Different Approaches of Measuring Skeletonized Radial Peripapillary Capillary Vessel Density in Glaucoma Patients

open access: yesFrontiers in Medicine, 2022
ObjectiveTo compare performance assessment of two methods of measuring radial peripapillary capillary (RPC) vessel density (VD) after skeletonization using MATLAB and Image J in glaucoma clinical setting.MethodsSeventy-three eyes of 73 glaucoma patients ...
Yiqin Guo   +6 more
doaj   +1 more source

Morphological feature extraction for statistical learning with applications to solar image data [PDF]

open access: yes, 2013
: Many areas of science are generating large volumes of digital image data. In order to take full advantage of the high-resolution and high-cadence images modern technology is producing, methods to automatically process and analyze large batches of such ...
Adams   +14 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Cascaded Thinning in Upscale and Downscale Representation for EEG Signal Processing

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Smoothing filters are widely used in EEG signal processing for noise removal while preserving signals’ features. Inspired by our recent work on Upscale and Downscale Representation (UDR), this paper proposes a cascade arrangement of some effective
Quang Manh Doan   +4 more
doaj   +1 more source

A Comparison of the Tortuosity Phenomenon in Retinal Arteries and Veins Using Digital Image Processing and Statistical Methods

open access: yesMathematics, 2023
The tortuosity of retinal blood vessels is an important phenomenon, and it can act as a biomarker in the diagnosis of several eye diseases. The study of abnormalities in the tortuosity of retinal arteries and veins provides ophthalmologists with ...
Sufian A. Badawi   +6 more
doaj   +1 more source

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