Results 41 to 50 of about 320,245 (358)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Getting Conspiratorial: Review of: Conspiracy Culture: From Kennedy to the X-files by Peter Knight [PDF]
, 2001 Peter Knight begins his foray into the conspiratorial corners of popular culture with the following provocation: conspiracy theories are no longer the “delusional rantings” of the fringe elements in society, but rather constitute “many people’s normal ...
Kuhlman, Martha
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Doubt and dogmatism in Cicero’s Academica
Archai: Revista de Estudos sobre as Origens do Pensamento Ocidental, 2019 The objective is to show the peculiar way in which Cicero’s philosophical thinking is original and distances itself from the main representatives of the New Academy: the Roman thinker does not practice epoche, nor does he assign any special role to it in
Alexandre Skvirsky
doaj +1 more source
On Dependency between Wishes and Perception
Дискурс, 2021 Introduction. Empirical studies of recent years convincingly show that the character of sensory perception can be influenced by non-cognitive mental states of the agent, such as her desires.
A. I. Ponomarev, K. G. Frolov
doaj +1 more source
Kevin McCain and Ted Poston’s Best Explanations [PDF]
, 2020 In this critical notice, I focus my attention on the chapters that deal with the explanationist response to ...
Cabrera, Frank
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Structuralism as a Response to Skepticism [PDF]
, 2018 Cartesian arguments for global skepticism about the external world start from the premise that we cannot know that we are not in a Cartesian scenario such as an evil-demon scenario, and infer that because most of our empirical beliefs are false in such a
Chalmers, David J.
core
Epicureanism and Skepticism about Practical Reason [PDF]
, 2020 Epicureans believe that death cannot harm the one who dies because they hold the existence condition, which states that a subject is able to be harmed only while they exist.
Frugé, Christopher
core
Bayesian Estimation Improves Prediction of Outcomes After Epilepsy Surgery
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We estimated the statistical power of studies predicting seizure freedom after epilepsy surgery. We extracted data from a Cochrane meta‐analysis. The median power across all studies was 14%. Studies with a median sample size or less (n ≤ 56) and a statistically significant result exaggerated the true effect size by a factor of 5.4, while the ...
Adam S. Dickey +4 more
wiley +1 more source