Results 41 to 50 of about 81,357 (292)

Epistemology and Ethics in Zhuangzi

open access: yesPhilosophies, 2021
On a prima facia reading, Zhuangzi seems to endorse some form of skepticism or relativism. This seems at odds with Zhuangzi as one of the two main sources of classical Daoism, considering the ideals of virtue and self-development promoted by that ...
S. Evan Kreider
doaj   +1 more source

Millennial Consumers’ Responses to Cause-Related Marketing in Support of LGBTQ Homeless Youth

open access: yesSocial Sciences, 2019
This study explored Millennial consumers’ responses to a cause-related marketing (CRM) initiative for a sensitive social cause—lesbian, gay, bisexual, transgender and queer (LGBTQ) homeless youth. Qualitative and quantitative research methods
Cammie Hensley   +2 more
doaj   +1 more source

Empirical research into the problem of other minds: How developmental social psychology can strengthen the Wittgensteinian attitudinal approach [PDF]

open access: yesBelgrade Philosophical Annual, 2014
My goal in this paper is to examine the Wittgensteinian attitudinal approach to the problem of other minds initially proposed by M.R.M. ter Hark (1991) and developed by Hyslop (1995). As some other Wittgensteinian approaches this one also starts with the
Radenović Ljiljana
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Query concerning the Specifics of the Problematic that Elicits Locke’s Essay, at I.i.2, 44 and I.i.7, 47

open access: yesLocke Studies, 2019
This is a query regarding what and whom Locke refers to in passages from Essay I.i.2 and I.i.7.
Bruce Merrill
doaj   +1 more source

'Layer-by-layer construction of the ancient history of China': Gu Jiegang's method and hypothesis

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2021
The article focuses on the establishment of the theoretical and methodological basis of the Chinese historical school of doubt in antiquity led by Gu Jiegang, a prominent historian. The study is driven and inspired by the growing research interest in the
S.G. Petrova
doaj   +1 more source

Skeptical hypotheses and moral skepticism [PDF]

open access: yesCanadian Journal of Philosophy, 2013
Moral skeptics maintain that we do not have moral knowledge. Traditionally they haven't argued via skeptical hypotheses like those provided by perceptual skeptics about the external world, such as Descartes' deceiving demon. But some believe this can be done by appealing to hypotheses like moral nihilism.
openaire   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Superintelligence Skepticism as a Political Tool

open access: yesInformation, 2018
This paper explores the potential for skepticism about artificial superintelligence to be used as a tool for political ends. Superintelligence is AI that is much smarter than humans.
Seth D. Baum
doaj   +1 more source

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