Results 231 to 240 of about 14,405,507 (294)

A metric for quantifying adaptation to successive disruptions. [PDF]

Sci Rep
van Steijn F, Aydin NY, Doorn N, Comes T.   +3 more
europepmc   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Structural Divergence Between the Moltbook AI‐Agent Network and Human Social Networks

Advanced Science, EarlyView.
Analysis of the Moltbook AI‐agent network reveals a striking combination of familiar global scaling and distinct internal organization. Attention is highly concentrated, reciprocity is limited, connected triads are suppressed, and communities are strongly modular.
Wenpin Hou, Zhicheng Ji
wiley   +1 more source

Complete Mitochondrial Genome of <i>Acartiella sinensis</i> Shen & Lee, 1963 (Copepoda, Calanoida) and Its Phylogeny. [PDF]

Animals (Basel)
Tang Q, Wang L, Li Y, Ning J, Liu S, Huang D, Zhu J, Wu X, Du F.   +8 more
europepmc   +1 more source

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source

The complete mitochondrial genome of the thrips predator <i>Montandoniola moraguesi</i> (Hemiptera: Anthocoridae) and its phylogenetic analysis. [PDF]

Mitochondrial DNA B Resour
Wang HW, Guo FY, Wang X.
europepmc   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Mitogenomic Analysis and Conservation Genetics of the Endangered Oriental Stork (<i>Ciconia boyciana</i>). [PDF]

Animals (Basel)
Chen XD, Wang YY, Xu ZM, Xiao L, Lu CH, Sun CH, Li CZ.   +6 more
europepmc   +1 more source

Mitochondrial genomes of Dactylogyrus wunderi (Monopisthocotyla: Dactylogyridae): structural features, codon usage patterns, and phylogenetic implications. [PDF]

BMC Genomics
Yang YY, Yue C, Zhang L, Xia SZ, Liu YJ, Wei NW, Hao CL.   +6 more
europepmc   +1 more source

Mitochondrial genomes and phylogenomic analysis of <i>Plectostylus broderipii</i> and <i>Bostryx erythrostoma</i> (Gastropoda, Stylommatophora, Orthalicoidea) from the Atacama Desert, Chile. [PDF]

Zookeys
Contreras-Díaz R, Barahona-Segovia RM, Catalán-Garrido R, Araya JF, Arias-Aburto M, Pizarro-Gacitúa C.   +5 more
europepmc   +1 more source