Results 91 to 100 of about 6,790,902 (292)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

"Stochastic Volatility Model with Leverage and Asymmetrically Heavy-Tailed Error Using GH Skew Student's t-Distribution Models" [PDF]

open access: yes
Bayesian analysis of a stochastic volatility model with a generalized hyperbolic (GH) skew Student's t-error distribution is described where we first consider an asymmetric heavy-tailed error and leverage effects.
Jouchi Nakajima, Yasuhiro Omori
core  

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma   +13 more
wiley   +1 more source

Modeling of thermally induced skew variations in clock distribution network [PDF]

open access: yes, 2011
Clock distribution network is sensitive to large thermal gradients on the die as the performance of both clock buffers and interconnects are affected by temperature.
Macii, Alberto   +5 more
core  

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu   +10 more
wiley   +1 more source

A new family of skewed slash distributions generated by the normal kernel

open access: yesStatistica, 2013
The present paper is a generalization of the recent paper by Nadaraja and Kotz (2003) (Skewed distributions generated by the normal kernel, “Statistics & Probability Letters’’, 65, pp. 269-277). The new family of univariate skewed slash distributions
Bindu Punathumparambath
doaj   +1 more source

Marginal Distributions of Random Vectors Generated by Affine Transformations of Independent Two-Piece Normal Variables [PDF]

open access: yes
Marginal probability density and cumulative distribution functions are presented for multidimensional variables defined by non-singular affine transformations of vectors of independent two-piece normal variables, the most important subclass of Ferreira ...
Maximiano Pinheiro
core  

A generalized skew two-piece skew-normal distribution

open access: yes
Skew-normal distribution, Generalized skew-normal distribution, Two-piece skew-normal distribution, Generalized two-piece skew-normal distribution, Generalized skew two-piece skew-normal distribution, Unimodality and bimodality, Orthant probability,
A. Jamalizadeh   +2 more
core   +1 more source

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