Results 111 to 120 of about 433,672 (329)

Efficient and Robust Standing Postures of Quadruped Robots

open access: yesAdvanced Robotics Research, EarlyView.
A calibrated static framework estimates load, optimizes torques, and adapts posture so quadruped robots stand efficiently and robustly under external payloads, achieving up to 50% lower torque demand. Inspired by the natural posture adjustments of animals under external loading, this article presents an optimization‐based framework for minimizing joint
Mohamad Kanaan   +5 more
wiley   +1 more source

A Note On Skew-Normal Distribution Approximation To The Negative Binomal Distribution

open access: yes, 2011
This article revisits the problem of approximating the negative binomial distribution. Its goal is to show that the skew-normal distribution, another alternative methodology, provides a much better approximation to negative binomial probabilities than ...
Lin, Jyh-Jiuan; Chang, Ching-Hui; Jou, Rosemary   +1 more
core  

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

A new class of Skew-Normal-Cauchy Distribution [PDF]

open access: yes, 2015
In this paper we study a new class of skew-Cauchy distributions inspired on the family extended two-piece skew normal distribution. The new family of distributions encompasses three well known families of distributions, the normal, the two-piece skew ...
Bolfarine, Heleno   +3 more
core   +1 more source

Construction and Applications of a Composite Model Based on Skew-Normal and Skew-t Distributions

open access: yesEconometrics
Financial return distributions often exhibit central asymmetry and heavy-tailed extremes, challenging standard parametric models. We propose a novel composite distribution integrating a skew-normal center with skew-t tails, partitioning the support into ...
Jingjie Yuan, Zuoquan Zhang
doaj   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

open access: yesAdvanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen   +7 more
wiley   +1 more source

Modeling asymmetric compositional data

open access: yesActa Scientiarum: Technology, 2014
Compositional data belong to the simplex sample space, but they are transformed to the sample space of the real numbers using the additive log-ratio transformation to allow the application of standard statistical techniques.
Ana Beatriz Tozzo Martins   +4 more
doaj   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang   +11 more
wiley   +1 more source

The Extended Half-Skew Normal Distribution

open access: yes, 2023
A new class of densities for modelling non-negative data, which is based on the skew-symmetric family of distributions proposed by Azzalini is introduced.We focus on the model generated by the skew-normal distribution, called Extended Half Skew-Normal ...
Barranco Chamorro, Inmaculada   +4 more
core  

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

open access: yesAdvanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu   +19 more
wiley   +1 more source

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