Results 121 to 130 of about 433,672 (329)

Alpha-Skew Generalized t Distribution [PDF]

open access: yes, 2015
The alpha-skew normal (ASN) distribution has been proposed recently in the literature by using standard normal distribution and a skewing approach. Although ASN distribution is able to model both skew and bimodal data, it is shortcoming when data has ...
Senoglu, Birdal   +2 more
core  

Classification Methods for the Serological Status Based on Mixtures of Skew-Normal and Skew-t Distributions

open access: yesMathematics
Gaussian mixture models are widely employed in serological data analysis to discern between seropositive and seronegative individuals. However, serological populations often exhibit significant skewness, making symmetric distributions like Normal or ...
Tiago Dias-Domingues   +2 more
doaj   +1 more source

Bimodal and nultimodal extensions of the normal and skew normal distributions

open access: yesRevstat Statistical Journal
0 ...
Gómez Déniz, Emilio   +2 more
openaire   +4 more sources

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

MCMC Bayesian Estimation of a Skew-GED Stochastic Volatily Model [PDF]

open access: yes
In this paper we present a stochastic volatility model assuming that the return shock has a Skew-GED distribution. This allows a parsimonious yet flexible treatment of asymmetry and heavy tails in the conditional distribution of returns.
Davide Raggi   +2 more
core  

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

open access: yesAdvanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin   +12 more
wiley   +1 more source

Confidence Intervals for True Scores Using the Skew-Normal Distribution

open access: yes, 2010
A recent comparative analysis of alternative interval estimation approaches and procedures has shown that confidence intervals (CIs) for true raw scores determined with the Score method—which uses the normal approximation to the binomial distribution ...
Miguel A. García-Pérez
core   +1 more source

The Family of Log-Skew-Normal Alpha-Power Distributions using Precipitation Data

open access: yesRevista Colombiana de Estadística, 2013
We present a new set of distributions for positive data based on a skew-normal alpha-power (PSN) model including a new parameter which in turn makes the log-skew-normal alpha-power (LPSN) model more flexible than both the log-normal (LN) model and log ...
GUILLERMO MARTÍNEZ-FLÓREZ   +2 more
doaj  

Home - About - Disclaimer - Privacy