Results 51 to 60 of about 139,023 (311)
Skewness in energy returns: estimation, testing and implications for tail risk
In this paper we estimate the skewness of the unconditional distribution of energy returns and test its statistical significance. We compare the performance of traditional and robust tests for skewness with those based on the implied unconditional ...
Ñíguez, T.M., Carnero, M.A., León, A.
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
On the Relationship Between the Gini Coefficient and Skewness
Skewness, a measure of the asymmetry of a distribution, is frequently employed to reflect a biologically important property. Another statistic, the Gini coefficient (GC), originally used to measure economic inequality, has been validated in measuring the
Meng Lian +4 more
doaj +1 more source
By resorting to the vector space structure of finite games, skew-symmetric games (SSGs) are proposed and investigated as a natural subspace of finite games. First of all, for two player games, it is shown that the skew-symmetric games form an orthogonal complement of the symmetric games.
Yaqi Hao, Daizhan Cheng
openaire +2 more sources
Skewed Compressed Caches [PDF]
Cache compression seeks the benefits of a larger cache with the area and power of a smaller cache. Ideally, a compressed cache increases effective capacity by tightly compacting compressed blocks, has low tag and metadata overheads, and allows fast lookups. Previous compressed cache designs, however, fail to achieve all these goals.
Sardashti, Somayeh +2 more
openaire +2 more sources
Does average skewness matter? Evidence from the Taiwanese stock market
This paper replicates Jondeau et al. (2019) on the topic of average skewness which is the average of monthly skewness values across firms. First, we consistently reproduce their main results and validate that average skewness negatively predicts the next-
Onishchenko, Olena +2 more
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
A Weighted Skew-Logistic Distribution with Applications to Environmental Data
Skewness and bimodality properties are frequently observed when analyzing environmental data such as wind speeds, precipitation levels, and ambient temperatures.
Isaac Cortés +2 more
doaj +1 more source

