Results 41 to 50 of about 139,023 (311)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Spatial Evolution of Skewness and Kurtosis of Unidirectional Extreme Waves Propagating over a Sloping Beach

open access: yesJournal of Marine Science and Engineering, 2022
The understanding of the occurrence of extreme waves is crucial to simulate the growth of waves in coastal regions. Laboratory experiments were performed to study the spatial evolution of the statistics of group-focused waves that have a relatively broad-
Iskander Abroug   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Weighted Ranked Set Sampling for Skewed Distributions

open access: yesMathematics
Ranked set sampling (RSS) is a useful technique for improving the estimator of a population mean when the sampling units in a study can be more easily ranked than the actual measurement. RSS performs better than simple random sampling (SRS) when the mean
Dinesh S. Bhoj, Girish Chandra
doaj   +1 more source

Effect of Shaft Surface Roughness on the Performance of Radial Lip Seals

open access: yesLubricants, 2018
Reduction of leakage from the shaft⁻radial lip seal conjunction is critical in ensuring enduring performance of entire lubrication system. This paper investigates leakage from three types of shaft surfaces, finished using different manufacturing ...
Emilia Kozuch   +4 more
doaj   +1 more source

Frequency distribution and genetic variability for forage yield attributing traits in oats (Avena sativa L.)

open access: yesElectronic Journal of Plant Breeding, 2022
An experiment was conducted with 125 germplasm accessions and five check varieties of Oat (Avena sativa L.) in augmented design during rabi, 2019-20. Nineteen quantitative traits were studied for the assessment of genetic variability.
Rashmi Toppo and Mayuri Sahu*
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Review of Fourth-Order Maximum Entropy Based Predictive Modeling and Illustrative Application to a Nuclear Reactor Benchmark: II. Best-Estimate Predicted Values and Uncertainties for Model Responses and Parameters

open access: yesEnergies
This work continues the review and illustrative application to energy systems of the “Fourth-Order Best-Estimate Results with Reduced Uncertainties Predictive Modeling” (4th-BERRU-PM) methodology.
Dan Gabriel Cacuci, Ruixian Fang
doaj   +1 more source

Skew Randić Matrix and Skew Randić Energy

open access: yesTransactions on Combinatorics, 2014
Let $G$ be a simple graph with an orientation $σ$, which assigns to each edge a direction so that $G^σ$ becomes a directed graph. $G$ is said to be the underlying graph of the directed graph $G^σ$. In this paper, we define a weighted skew adjacency matrix with Randć weight, the skew Randić matrix ${\bf R_S}(G^σ)$, of $G^σ$ as the real skew symmetric ...
Gu, Ran, Huang, Fei, Li, Xueliang
openaire   +3 more sources

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