Results 61 to 70 of about 383,562 (303)

Effect of Shaft Surface Roughness on the Performance of Radial Lip Seals

Lubricants, 2018
Reduction of leakage from the shaft⁻radial lip seal conjunction is critical in ensuring enduring performance of entire lubrication system. This paper investigates leakage from three types of shaft surfaces, finished using different manufacturing ...
Emilia Kozuch, Petros Nomikos, Ramin Rahmani, Nick Morris, Homer Rahnejat   +4 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Review of Fourth-Order Maximum Entropy Based Predictive Modeling and Illustrative Application to a Nuclear Reactor Benchmark: II. Best-Estimate Predicted Values and Uncertainties for Model Responses and Parameters

Energies
This work continues the review and illustrative application to energy systems of the “Fourth-Order Best-Estimate Results with Reduced Uncertainties Predictive Modeling” (4th-BERRU-PM) methodology.
Dan Gabriel Cacuci, Ruixian Fang
doaj   +1 more source

Non-sinusoidal current-phase relationship in Josephson junctions from the 3D topological insulator HgTe

, 2014
We use Superconducting QUantum Interference Device (SQUID) microscopy to characterize the current-phase relation (CPR) of Josephson Junctions from 3-dimentional topological insulator HgTe (3D-HgTe).
Brüne, Christoph, Buhmann, Hartmut, Gould, Charles, Hankiewicz, Ewelina M., Kirtley, John R., Maier, Luis, Molenkamp, Laurens W., Moler, Kathryn A., Sochnikov, Ilya, Tkachov, Grigory, Watson, Christopher A.   +10 more
core   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

On the Relationship Between the Gini Coefficient and Skewness

Ecology and Evolution
Skewness, a measure of the asymmetry of a distribution, is frequently employed to reflect a biologically important property. Another statistic, the Gini coefficient (GC), originally used to measure economic inequality, has been validated in measuring the
Meng Lian, Long Chen, Cang Hui, Fuyuan Zhu, Peijian Shi   +4 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

A Weighted Skew-Logistic Distribution with Applications to Environmental Data

Mathematics
Skewness and bimodality properties are frequently observed when analyzing environmental data such as wind speeds, precipitation levels, and ambient temperatures.
Isaac Cortés, Jimmy Reyes, Yuri A. Iriarte   +2 more
doaj   +1 more source