Results 41 to 50 of about 318 (202)

Skidding of fir roundwood by Timberjack 240C from selective forests of Gorski Kotar

open access: yesCroatian Journal of Forest Engineering, 2005
The aim of the research was to determine the productivity of the cable skidder Timberjack 240C equipped with double-drum winch Konrad Adler HY 16 during skidding of fir roundwood from the Croatian mountainous selective forests of fir and beech.
Anton Sabo, Tomislav Poršinsky
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Felling and skidding damage to residual trees following selection cutting in Caspian forests of Iran

open access: yesJournal of Forest Science, 2013
The felling and skidding damage to residual trees was investigated in a selectively cutting operation in the Caspian forest of Iran. The logging operation was performed by chainsaw and cable skidder.
F. Tavankar, B. Majnounian, A.E. Bonyad
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

EFFECT OF TRAFFIC INTENSITIES OF A DIRECTIONAL FELLER AND SKIDDER ON THE COMPACTION OF A BRUNO NITISOL

open access: yesRevista Árvore
This study evaluated the compaction of a Bruno Nitisol caused by traffic intensities by a directional feller and skidder used to wood harvesting in a Pinus taeda stand. Data were collected at a forest company located in Parana State, Brazil. Samples were
Tamara Izabel de Andrade Payá   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Productivity Analysis of MB Trac 900 Skidder at Hauling of Beech Timber

open access: yesForestist, 2009
Tlıis study was done in beech stands in Gölköy Forest D istrict in O rdu forest adm inistratioıı. Tim ber yvas skidded uphill on skid strip. Time ıneasurem ents \vere done wlıile ıvorking skidder and collected data was carried out by statistical ...
Eyyüp Atıcı, Tolga Öztürk
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy