Results 111 to 120 of about 2,203,706 (318)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Research Skills

, 2010
This OER is intended to assist with advice and guidance to students on Research Skills, including writing Research Proposals, conducting a literature review, research ethics and preparation for a viva.
Student Development and Support Service
core  

Investigating the Level of Mathematics Anxiety among Junior High School Pupils

MEJ (Mathematics Education Journal)
Mathematics is a fascinating and perplexing subject that is constantly evolving in a variety of scientific fields. Naturally, it is amazing and beautiful to use mathematics to solve a real-life problem and comprehend it.
David Koomson, Francis Ohene Boateng, Ebenezer Kwesi Lotey   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

National Employer Skills Survey, 1999-2009: Secure Access

, 2011
copyright UK Data Service and data collection copyright owner.The National Employer Skills Survey (NESS) collects data about the skills of the workforce of firms in England.
Learning and Skills Council, UK Commission for Employment and Skills   +1 more
core   +2 more sources

Artificial intelligence in automated semen analysis: a systematic review of technical performance and clinical validity

Middle East Fertility Society Journal
Background Male infertility accounts for approximately 40–50% of all infertility cases worldwide, with semen analysis remaining the cornerstone of diagnosis.
Ravi Yadav, Debasrita Banerjee
doaj   +1 more source

Research on Collaborative Optimization Method of CCHP Regional Integrated Energy System Based on Improved Multivariate Universe Algorithm

IEEE Access
Aiming to address the prevailing issue where Cold Heat and Power (CCHP)-type integrated energy systems are primarily optimized for either economy or environmental friendliness, this paper conducts an exhaustive synergistic optimization analysis of the ...
Dahai Xu, Changle Yu, Wenwen Li, Su Zhang, Zhengda Li, Zhihui Qu, Pengtao Li, Xingfan Han   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Ensuring flexible optical intubation skills using a portable virtual reality simulator – a validation study

BMC Anesthesiology
Background Anesthesiologists must be able to perform flexible optical intubation (FOI) in challenging cases, but the skill is difficult to master and cannot be adequately taught using the traditional apprenticeship model.
Mingjuan Sun, Xiaomei Guo, Qiong Qin, Huimin Liu, Hongyan Fang, Chengyun Wu, Zheng Wang, Lars Konge, Rong Zhao   +8 more
doaj   +1 more source

Influence of AI learning analytics and virtual laboratory use on STEM conceptual understanding: the mediating role of cognitive engagement

Frontiers in Education
PurposeThe study investigated the effects of AI learning analytics and virtual laboratory use on STEM conceptual understanding and the mediating role of cognitive engagement.Methodology/design/approachThe study adopted a cross-sectional correlational ...
Shadrach Mensah, Bright Asare, Samuel Kwadwo Aboagye   +2 more
doaj   +1 more source