Results 131 to 140 of about 2,960,039 (306)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Presentation skills - Face-to-face activities

open access: yes, 2013
Handouts and resources for delivering a face-to-face session on presentation skills.
Skills@Library
core  

PLUS tutorials with complementary Skills Development Lectures

open access: yes, 2014
These materials are used in a second year Political Studies class to continue a students' skills development. A continuation from the first year PLUS tuts, these tutorials are linked with Skills Development Lectures (SDLs).
Duthie, Shawn   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Undergraduate Skills Audit

open access: yes, 2010
Academic skills audit to support personal development ...
Judith Tillson, Staffordshire University
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Guided teaching, technology integration, and learner engagement as predictors of mathematical problem-solving ability: A structural equation modeling study

open access: yesInternational Journal of Didactic Mathematics in Distance Education
Mathematical problem-solving remains a critical yet persistently underperformed competency among senior high school students in Ghana. This study examined the simultaneous influence of guided teaching approaches, technology integration, and learner ...
Mary Gyenyn   +2 more
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The Skilled Phlebotomist

open access: yesArchives of Pathology & Laboratory Medicine, 2006
LIPPI, Giuseppe   +3 more
openaire   +4 more sources

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