Results 121 to 130 of about 5,711,956 (312)
Digital HealthIntroduction Telehealth is crucial to the provision of high-quality treatment of critically unwell patients in rural areas. Our aim was to explore the benefits and limitations of a mixed reality (MR) headset for clinician-to-clinician telehealth in a ...
Chiara Santomauro +6 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Journal of Computing Research and InnovationThe need for programmability and backup automation in modern network administration has become increasingly critical. In environments that facilitate and heavily depend on essential network operations, such as hospitals, ensuring secure, stable, and ...
Franco Osei-Wusu +5 more
doaj +1 more source
Skills Academy research report [PDF]
, 2010 "This research was commissioned by the Welsh Assembly Government in July 2009 in order to review the development, operation and sustainability of Skills Academy networks across the UK and other relevant countries, to determine the strengths and ...
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Future Business JournalIt has been crucial to solve the service delivery problem since civil society emerged. Even though several barriers to top-quality public service exist, there is little research based on evidence about how digital technologies help address these barriers
Masud Ibrahim +3 more
doaj +1 more source
The Skills Framework at key stage 2: an evaluation of the impact of the non-statutory Sskills framework for 3 to 19-year-olds in Wales at key stage 2 [PDF]
, 2011 1 The non-statutory Skills framework for 3 to 19-year-olds in Wales provides guidance on developing pupils’ skills in thinking, communication, ICT and number.
Jones, Ann, Miles, Liz, Newton, Lynda
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Discover Mechanical EngineeringThis study investigates the coupled thermo-tribological performance of aluminum matrix composite (Al7075–6 wt.% ZrB2) hydrodynamic journal bearings (HDJBs) lubricated with TiO2-enhanced SAE 20W40 nanolubricants.
Amol B. Gaikwad +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source