Results 141 to 150 of about 2,203,706 (318)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Updating the adult and literacy life skills survey: estimating change in skills distribution since 2006 [PDF]
This paper firstly estimates the effect of population changes since 2006 on the skills distribution of the population. Secondly, the paper estimates the reach of adult literacy and numeracy programmes by skills levels in the adult population.
David Earle
core
It has been crucial to solve the service delivery problem since civil society emerged. Even though several barriers to top-quality public service exist, there is little research based on evidence about how digital technologies help address these barriers
Masud Ibrahim +3 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Skills for Life Series: Empathy & Compassion
Empathy and compassion are vital skills for emotional and social development, motivating prosocial behaviors and effective conflict resolution. Empathy involves understanding others\u27 emotions, while compassion drives actions to alleviate their ...
Inter-American Development Bank
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
More effective skills utilisation : shifting the terrain of skills policy in Scotland
This paper examines shifts in skills policy in Scotland towards emphasising the importance of effective skills utilisation. Turning policy into practice, however, requires a better understanding than currently exists of skills utilisation in order to ...
Findlay, Patricia, Warhurst, Chris
core

