Results 141 to 150 of about 2,960,039 (306)
Digital HealthIntroduction Telehealth is crucial to the provision of high-quality treatment of critically unwell patients in rural areas. Our aim was to explore the benefits and limitations of a mixed reality (MR) headset for clinician-to-clinician telehealth in a ...
Chiara Santomauro +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Skills for Life Series: Empathy & Compassion
Empathy and compassion are vital skills for emotional and social development, motivating prosocial behaviors and effective conflict resolution. Empathy involves understanding others\u27 emotions, while compassion drives actions to alleviate their ...
Inter-American Development Bank
core +1 more source
Skills and earnings revisited [PDF]
, 2005 Regression and neural network models of wage determination are constructed where the explanatory variables include detailed information about skills. People skills, strategic skills, and IT skills all carry strong and significant wage premia; problem ...
Johnes, G
core
Discover Concrete and CementThe cement industry contributes almost 8% of global CO₂ emissions, creating an urgent need to develop scalable low-carbon substitutes for ordinary Portland cement (OPC). Supplementary cementitious materials (SCMs) based on agricultural ashes have emerged
Adamu Wahab +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Skills upgrading needs : the challenge for employers and training providers in Scotland and Northern Ireland [PDF]
, 2007 his report presents the findings of research on meeting employers’ skills upgrading needs through engagement with Further Education (FE) and commercial vocational education and training (VET) providers in Scotland and Northern Ireland. The research
Greig, Malcolm +7 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source