Results 121 to 130 of about 5,010,256 (252)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Navigating converging pathways of co-infection: an integrated epidemiological insight into hepatitis B and malaria among pregnant women in the middle belt of Ghana

BMC Infectious Diseases
Background Viral hepatitis B (HBV) and malaria during pregnancy pose significant health risks. This is because both HBV and Plasmodium undergo certain developmental stages in the liver.
Dennis Bardoe, Daniel Hayford, Robert Bagngmen Bio, Denis Dekugmen Yar   +3 more
doaj   +1 more source

Do environmental CSR practices promote corporate social performance? The mediating role of green innovation and corporate image

Cleaner and Responsible Consumption
This article examined how Environmental Corporate Social Responsibility (ECSR) activities directed through green innovation influence corporate image and corporate social performance.
Edward Fosu, Francis Fosu, Noah Akyina, Deborah Asiedu   +3 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Assessing the prevalence, risk factors, and socio-demographic predictors of malaria among pregnant women in the Bono East Region of Ghana: a multicentre hospital-based mixed-method cross-sectional study

Malaria Journal
Background Malaria is one of the world’s most lethal vector-borne diseases, causing significant health burdens in endemic countries. Several studies on the prevalence of malaria among pregnant women in Ghana have been conducted in various parts of the ...
Dennis Bardoe, Robert Bagngmen Bio, Denis Dekugmen Yar, Daniel Hayford   +3 more
doaj   +1 more source

Strategic foresight and AI readiness: mediating roles of digital transformation capability and students’ perceptions of institutional agility

Frontiers in Artificial Intelligence
PurposeThe study aimed to investigate the mediating roles of digital transformation capability and students’ perceptions of institutional agility on the relationship between strategic foresight and AI readiness in higher education.Methodology/design ...
Bright Asare, Sadri Alija, Yarhands Dissou Arthur, Francis Ohene Boateng   +3 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Malaria in pregnancy: a holistic exploration of synergistic association through environmental, sociocultural, and socioeconomic lenses in Pru east municipality, Ghana

Malaria Journal
Background Malaria in pregnancy (MiP) is responsible for several maternal and neonatal complications. Despite the renewed dedication towards elimination and eradication, it is still endemic in Ghana.
Dennis Bardoe, Daniel Hayford, Robert Bagngmen Bio, Ernest Osei   +3 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source