Results 11 to 20 of about 522,886 (274)
Sirtuins in Skin and Skin Cancers [PDF]
The sirtuins are a family of proteins that comprise class III of the histone deacetylases. These NAD+-dependent proteins have been found to be intricately involved in a variety of important and skin-relevant cellular functions and processes, including aging, UV damage response, oxidative stress, and wound repair.
Christine Gaby Azer Philippe+5 more
openaire +3 more sources
Development of a Rapid and Confirmatory Method to Identify Ganoderic Acids in Ganoderma Mushrooms
To examine the composition of lanostanoids in Ganoderma lucidum, we have developed a liquid chromatography-mass spectrometry (LC-MS) method by using the ganoderic acids isolated in our laboratory as reference standards.
Hao Howard Sun, Ying eQi, Lingling eZhao
doaj +1 more source
Effect of skin-to-skin contact on stimulation threshold and dosimetry [PDF]
The human dosimetry for electromagnetic field exposure is an essential task to develop exposure guidelines/standards for human safety as well as product safety assessment. At frequencies from a few hundred Hz to 10 MHz, the adverse effect to be protected is the stimulation of the peripheral nervous system. The in situ electric field in the skin is used
arxiv +1 more source
Key changes in chromatin mark mammalian epidermal differentiation and ageing
Dynamic shifts in chromatin states occur during embryonic epidermal development to support diverse epigenetic pathways that regulate skin formation and differentiation.
Christabel Thembela Dube+2 more
doaj +1 more source
Higher-order non-Hermitian skin effect [PDF]
The non-Hermitian skin effect is a unique feature of non-Hermitian systems, in which an extensive number of boundary modes appear under the open boundary conditions. Here, we discover higher-order counterparts of the non-Hermitian skin effect that exhibit new boundary physics.
arxiv +1 more source
Treatment with immune checkpoint inhibitors (ICIs) has improved the prognosis of melanoma patients. However, ICIs can cause an overactivation of the immune system followed by diverse immunological side effects known as immune-related adverse events (irAE)
Alisa Lepper+6 more
doaj +1 more source
Assessing the Generalizability of Deep Neural Networks-Based Models for Black Skin Lesions [PDF]
Melanoma is the most severe type of skin cancer due to its ability to cause metastasis. It is more common in black people, often affecting acral regions: palms, soles, and nails. Deep neural networks have shown tremendous potential for improving clinical care and skin cancer diagnosis.
arxiv +1 more source
Multi-class Skin Cancer Classification Architecture Based on Deep Convolutional Neural Network [PDF]
Skin cancer detection is challenging since different types of skin lesions share high similarities. This paper proposes a computer-based deep learning approach that will accurately identify different kinds of skin lesions. Deep learning approaches can detect skin cancer very accurately since the models learn each pixel of an image. Sometimes humans can
arxiv +1 more source
Endogenous and microbial volatile organic compounds in cutaneous health and disease [PDF]
Human skin is a region of high metabolic activity where a rich variety of biomarkers are secreted from the stratum corneum. The skin is a constant source of volatile organic compounds (VOCs) derived from skin glands and resident microbiota. Skin VOCs contain the footprints of cellular activities and thus offer unique insights into the intricate ...
arxiv +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen+3 more
wiley +1 more source