Results 121 to 130 of about 492,394 (350)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

open access: yesAdvanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen   +30 more
wiley   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

open access: yesAdvanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park   +10 more
wiley   +1 more source

In Vivo Monitoring Of Drug Penetration In Human Skin Using Reflectance Technique

open access: yesIndian Journal of Dermatology, 2002
Apparent drug penetration by skin was non-invasively using light monitored reflectance at 632.8 nm. The method uses a commercially available low-power He-Ne laser device and a multimode optical fibre.
Alattar Hameed A   +2 more
doaj  

An overview of the crash dynamics failure behavior of metal and composite aircraft structures [PDF]

open access: yes
An overview of failure behavior results is presented from some of the crash dynamics research conducted with concepts of aircraft elements and substructure not necessarily designed or optimized for energy absorption or crash loading considerations ...
Boitnott, Richard L.   +3 more
core   +1 more source

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

open access: yesAdvanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim   +13 more
wiley   +1 more source

An evaluation of properties related to wear time of four dressings during a five-day period [PDF]

open access: yes, 2015
This study evaluated skin tolerance and other properties relating to wear time, such as conformability and comfort, pain on dressing removal, adhesion and premature detachment, of four advanced hydrated dressings applied to the knees and elbows of 22 ...
Bielfeldt, Stephen   +2 more
core  

Catalytic TiO2 with Self‐Assembled Monolayer for Highly Sensitive, Selective, and Non‐Invasive Monitoring of Sweat L‐Cysteine

open access: yesAdvanced Functional Materials, EarlyView.
A self‐assembled monolayer of 3‐mercaptopropyltrimethoxysilane (MPTS) molecular receptor and titanium oxide‐modified carbon cloth (MPTS/TiO2/CC) was synthesized for the specific detection of sweat L‐cysteine, which is associated with the precision neutrition, cardiovascular system and neuro system.
Xiangjie Chen   +11 more
wiley   +1 more source

Using Imiquimod-Induced Psoriasis-Like Skin as a Model to Measure the Skin Penetration of Anti-Psoriatic Drugs.

open access: yesPLoS ONE, 2015
ObjectivePsoriasis is a chronic inflammatory skin disease and topical therapy remains a key role for treatment. The aim of this study is to evaluate the influence of psoriasis-like lesions on the cutaneous permeation of anti-psoriatic drugs.MethodsWe ...
Yin-Ku Lin   +4 more
doaj   +1 more source

Bilayer Solar Crystallizer by a Directional Liquid Transport Fabric for Stable Brine Treatment and Ion Recycling

open access: yesAdvanced Functional Materials, EarlyView.
The unique brine transportation and salt crystallization behavior, that is, the salt is preferred to be crystallized on the surface of the directional liquid transportation fabric, is discovered and investigated in this work. Abstract Directional and asymmetric liquid transport (DALT) materials are promising for human moisture management and ...
Zhang Hanchao   +7 more
wiley   +1 more source

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