Results 111 to 120 of about 13,443 (164)

Skin Absorption of Anions: Part One. Methodology for In Vitro Cutaneous Absorption Measurements

Pharmaceutical Research, 2016
International audienceMeasurement of skin absorption of ions requires specific experimental protocols regarding the use of pig skin as a model, the viability of excised skin in water medium over 24 h, the presence of endogenous ions, and evaluation of ...
Stephanie Briancon, Yves Chevalier, Marie-Alexandrine Bolzinger   +2 more
exaly   +2 more sources

Reconstructed skin models as emerging tools for drug absorption studies

Expert Opinion on Drug Metabolism and Toxicology, 2013
INTRODUCTION: As humans can come into contact with xenobiotics intentionally or accidentally, knowledge about the skin absorption of these substances is crucial and requires reliable models and test procedures.
Küchler, S., Friess, W., Strüver, K.
exaly   +2 more sources

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Skin Absorption of Inorganic Lead (PbO) and the Effect of Skin Cleansers

Journal of Occupational and Environmental Medicine, 2006
The aim of this study was to investigate the percutaneous penetration of lead oxide (PbO) powder and the effect of rapid skin decontamination with two different detergents.Franz cells were used to study in vitro PbO skin penetration through human skin during a 24-hour period.
LARESE FILON, FRANCESCA, BOENIGER M, MAINA G, ADAMI, GIANPIERO, SPINELLI P, DAMIAN A.   +5 more
openaire   +3 more sources

Absorption of Lawsone Through Human Skin

Cutaneous and Ocular Toxicology, 2007
Lawsone (2-hydroxy-1,4-naphthoquinone) is the principal color ingredient in henna, a color additive approved with limitations for coloring hair by the Food and Drug Administration (FDA) under 21 CFR 73.2190. In 2002, the scientific committee on cosmetics and non-food products (SCCNFP), now known as the scientific committee for consumer products (SCCP),
Margaret E K, Kraeling, Robert L, Bronaugh, Connie T, Jung   +2 more
openaire   +2 more sources

PERMEABILITY AND ABSORPTIVITY OF THE SKIN

Archives of Dermatology, 1939
Because of the systemic and local effects of the cutaneous application of various medicaments, the permeability and absorptivity of the skin are of particular importance to the dermatologist. As far back as 1809 Mussey1proved that after topical application of certain drugs to the unbroken skin these drugs were found in the urine, and in 1901 ...
openaire   +1 more source

The Absorption of Benzene through Human Skin

International Journal of Occupational and Environmental Health, 2000
Abstract : As a result of the proliferation of benzene solutions in several procuction technologies and prolonged exposure poisonings, the question about skin as a way of absorption has re-emerged with respect to the direction of preventive measures and the necessity to clarify the observed clinical signs of absorption.
J, Hanke, T, Dutkiewicz, J, Piotrowski
openaire   +2 more sources

Percutaneous absorption of vapors in human skin

Cutaneous and Ocular Toxicology, 2010
The absorption of vapors through the skin is an important issue because exposure of skin to chemicals in the ambient air occurs at all times. In regards to occupational health, accurately quantifying percutaneous absorption is crucial for worker health and safety.Review the available data regarding the percutaneous absorption of vapors in humans.We ...
Balvinder, Rehal, Howard, Maibach
openaire   +2 more sources

Skin absorption in vitro of glycol ethers

International Archives of Occupational and Environmental Health, 1999
The increased use of glycol ethers (GEs) for water-based paints and cleaning products, combined with a lack of information about many of these products, particularly with regard to the effects of percutaneous exposure, led us to evaluate the skin absorption rates of a group of glycol ethers in vitro.Skin permeation was calculated using the Franz cell ...
LARESE FILON, FRANCESCA, FIORITO A, ADAMI, GIANPIERO, BARBIERI, PIERLUIGI, COCEANI N, BUSSANI, ROSSANA, REISENHOFER, EDOARDO   +6 more
openaire   +3 more sources

Skin barrier function for regulatory skin absorption tests and effects on testosterone and sucrose absorption

Toxicology in Vitro
In vitro absorption through human skin is a critical component in the safety assessment of chemicals, crop protection products, consumer healthcare products and cosmetics. A barrier integrity assay is used to identify skin samples which are potentially damaged.
Thomas, Brackin, Heather, Gayes, Ian, Johnson, David, Fox, Clive, Roper   +4 more
openaire   +2 more sources

Percutaneous absorption of water in skin: a review

Reviews on Environmental Health, 2014
Abstract Background: The stratum corneum has a wide variety of important functions, including host protection from foreign chemicals and bacteria, water loss prevention, and body temperature regulation. While water absorption studies on healthy intact skin are abundant, data on the percutaneous absorption of water in ...
Collin M, Blattner, Garett, Coman, Nicholas R, Blickenstaff, Howard I, Maibach   +3 more
openaire   +2 more sources