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Absorption of hexavalent chromium by skin in man
Archives of Toxicology, 1981Absorption by skin of hexavalent chromium from aqueous solutions of sodium chromate in man was investigated. It was found that the amount of chromium absorbed was related to the concentration of Cr6+ in solution and to time of exposure. For 0.01, 0.1, and 0.2 molar solutions of chromium, skin absorption rates during 1 h exposure were 1.1, 6.5, and 10.0
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Annales pharmaceutiques francaises, 1993
Transdermal penetration of drugs is currently much studied because it presents several attractive aspects, avoiding first past effects and offering means of immediate breaking of the therapeutic in case of hitch. But it must overcome the very efficient hindrance of the epidermal barrier.
C, Durandeau +3 more
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Transdermal penetration of drugs is currently much studied because it presents several attractive aspects, avoiding first past effects and offering means of immediate breaking of the therapeutic in case of hitch. But it must overcome the very efficient hindrance of the epidermal barrier.
C, Durandeau +3 more
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Absorption of materials by or through the living skin
International Journal of Cosmetic Science, 1985SynopsisThe skin comes into contact with a large range of materials either deliberately or inadvertently. It should be possible to predict the exact transport rates of these materials through the skin as a function of the physicochemical properties of the different compounds.
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Critical reviews in therapeutic drug carrier systems, 1993
When we try to maximize drug flux through the skin, we usually meet major difficulties because of the impervious nature of the stratum corneum. A popular solution incorporates penetration enhancers into transdermal products. Such materials ideally possess the sole property of reversibly reducing the barrier resistance of the horny layer, allowing the ...
A C, Williams, B W, Barry
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When we try to maximize drug flux through the skin, we usually meet major difficulties because of the impervious nature of the stratum corneum. A popular solution incorporates penetration enhancers into transdermal products. Such materials ideally possess the sole property of reversibly reducing the barrier resistance of the horny layer, allowing the ...
A C, Williams, B W, Barry
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Paraquat Poisoning by Skin Absorption: A Review
Human Toxicology, 1988All reported cases of paraquat poisoning by absorption through the skin are briefly reviewed. It is concluded that, while paraquat cannot be absorbed significantly through intact human skin, damage to the skin, either by paraquat itself or by other means, will permit greater systemic absorption and possibly poisoning.
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Metal Nanoparticles Skin Absorption
Dermatitis®, 2011LARESE FILON, FRANCESCA +3 more
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Reflections on the OECD guidelines for in vitro skin absorption studies
Regulatory Toxicology and Pharmacology, 2020Aurélie Berthet +2 more
exaly
Skin absorption of inorganic nanoparticles and their toxicity: A review
European Journal of Pharmaceutics and Biopharmaceutics, 2023Maria Vergara-Barberán +2 more
exaly