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Guidance on dermal absorption [PDF]
EFSA Journal, 2017 This guidance on the assessment of dermal absorption has been developed to assist notifiers, users of test facilities and Member State authorities on critical aspects related to the setting of dermal absorption values to be used in risk assessments of ...
European Food Safety Authority (EFSA) +11 more
doaj +6 more sources
Guidance on Dermal Absorption [PDF]
EFSA Journal, 2012 This guidance on the assessment of dermal absorption has been developed to assist notifiers, users of test facilities and Member State authorities on critical aspects related to the setting of dermal absorption values to be used in risk assessments of ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
doaj +2 more sources
Effect of Application Amounts on In Vitro Dermal Absorption Test Using Caffeine and Testosterone
Pharmaceutics, 2021 Dermal absorption of chemicals is a key factor in risk assessment. This study investigated the effects of different amounts of application on dermal absorption and suggested an appropriate application dose for proper dermal absorption.
Jueng-Eun Im +5 more
doaj +3 more sources
Toxics, 2022 The cosmetic industry has flourished in recent years. Accordingly, the safety of cosmetic ingredients is increasing. Bromochlorophene (BCP) is a commonly used cosmetic preservative.
Yong-Jae Lee +4 more
doaj +3 more sources
Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children
Pharmaceutics, 2022 The higher skin surface area to body weight ratio in children and the prematurity of skin in neonates may lead to higher chemical exposure as compared to adults.
Yejin Esther Yun +3 more
doaj +3 more sources
Analytical Method Development and Dermal Absorption of Pyrogallol, a Hair Dye Ingredient
Toxics, 2022 Pyrogallol is an ingredient in hair dye. Its concentration in hair dye is managed at less than 2.0% in Korea. There have been no reports on the dermal absorption rate of pyrogallol.
Yu-Jin Kim +5 more
doaj +1 more source
Ethanol is indispensable for virucidal hand antisepsis and without toxic risks in daily use
GMS Hygiene and Infection Control, 2023 The approval of ethanol by the Biocidal Products Regulation has been under evaluation since 2007 due to controversial opinions on the risk assessment.
Kramer, Axel +3 more
doaj +1 more source
Race, pigmentation, and the human skin barrier—considerations for dermal absorption studies
Frontiers in Toxicology, 2023 A functional human skin barrier is critical in limiting harmful exposure to environmental agents and regulating the absorption of intentionally applied topical drug and cosmetic products.
Alec T. Salminen +2 more
doaj +1 more source
Early-Life Exposure to Formaldehyde through Clothing
Toxics, 2022 Clothes contain a wide range of chemicals, some of them potentially hazardous. Recently, there has been a growing interest in eco-friendly clothing, including the use of organic cotton.
Marta Herrero +5 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Physiologically based pharmacokinetic (PBPK) models are widely accepted tools utilised to describe and predict drug pharmacokinetics (PK). This includes the use of dermal PBPK models at the regulatory level including virtual bioequivalence (VBE) studies.
J. F. Clarke +4 more
doaj +1 more source