Assessment of new scientific studies on human in vitro dermal absorption [PDF]
EFSA Journal, 2015 This EFSA scientific report describes the results from the evaluation of new human in vitro studies on dermal absorption made available by European Crop Protection Association (ECPA) and the German public organisation Bundesinstitut für Risikobewertung ...
EFSA Working Group on Dermal Absorption
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Variability Between Datasets and Statistical Approaches—Rethinking Estimation of Default Dermal Absorption Values for Risk Assessment [PDF]
ToxicsIn risk assessment, deriving dermal absorption values is essential for evaluating plant protection products. Applicants submit study data, which authorities assess during the authorisation process.
Veronika Städele +2 more
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Investigation of the Dermal Absorption and Irritation Potential of Sertaconazole Nitrate Anhydrous Gel [PDF]
Pharmaceutics, 2016 Effective topical therapy of cutaneous fungal diseases requires the delivery of the active agent to the target site in adequate concentrations to produce a pharmacological effect and inhibit the growth of the pathogen.
Mahima Manian +3 more
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Fatal Dermal Absorption of Organophosphate Insecticide
ProceedingsOrganophosphate compounds are one of the leading causes of death due to poisoning worldwide due to their easy accessibility as insectides and pesticides.
Shankar M Bakkannavar, Vinod C Nayak
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Scientific Opinion on the Science behind the Revision of the Guidance Document on Dermal Absorption
EFSA Journal, 2011 This opinion provides the relevant data, evaluations and references that support the criteria proposed in the new draft guidance needed to facilitate assessment of dermal absorption of plant protection products (PPPs) under Directive 91/414/EEC[1] and ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
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Dermal Permeability of Perfluorohexane Sulfonic Acid (PFHxS) and Perfluorohexanoic Acid (PFHxA) in Varying Vehicles and the Effects on Skin Integrity in a Reconstructed Human Epidermis Model [PDF]
ToxicsPer- and polyfluoroalkyl substances (PFAS) are widespread environmental contaminants associated with adverse health effects, yet dermal exposure remains poorly characterized.
Lisa M. Weatherly +7 more
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Scim-phenylenediamine sulfate (mPDS) is used as an oxidative hair dye intermediate and is permitted in cosmetic products in Korea at concentrations up to 3%. However, quantitative data on its dermal absorption remain limited.
Han Nah Chung +5 more
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A new conceptional model for deriving average dermal absorption estimates from studies with multiple tested concentrations for non-dietary risk assessment of pesticides [PDF]
Archives of Toxicology, 2022 Christiane Wiemann +2 more
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Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases [PDF]
Journal of Occupational Medicine and Toxicology, 2006 There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals.
Angerer Jürgen +3 more
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Early-Life Exposure to Formaldehyde through Clothing
Toxics, 2022 Clothes contain a wide range of chemicals, some of them potentially hazardous. Recently, there has been a growing interest in eco-friendly clothing, including the use of organic cotton.
Marta Herrero +5 more
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