Results 11 to 20 of about 965,091 (147)

Fatal Dermal Absorption of Organophosphate Insecticide

Proceedings
Organophosphate compounds are one of the leading causes of death due to poisoning worldwide due to their easy accessibility as insectides and pesticides.
Shankar M Bakkannavar, Vinod C Nayak
doaj   +2 more sources

Analysis of finite dose dermal absorption data:Implications for dermal exposure assessment [PDF]

, 2014
A common dermal exposure assessment strategy estimates the systemic uptake of chemical in contact with skin using the fixed fractional absorption approach: the dermal absorbed dose is estimated as the product of exposure and the fraction of applied ...
Dotson, G. Scott, Sahmel, Jennifer, Wilkinson, Simon, Kasting, Gerald B., John C Kissel, Kasting, Gerald B, Sean Semple, H Frederick Frasch, Simon Wilkinson, Bunge, Annette L., Gerald B Kasting, Jennifer Sahmel, Annette L Bunge, Cherrie, John W.; id_orcid, Cherrie, John W, Kissel, John C., Frasch, H. Frederick, Kissel, John C, Frasch, H Frederick, G Scott Dotson, John W Cherrie, Chen-Peng Chen, Bunge, Annette L, Dotson, G Scott, Chen, Chen-Peng, Semple, Sean, Chen, Chen Peng   +26 more
core   +1 more source

In vitro dermal absorption of carfentanil

Toxicology in Vitro, 2020
There is growing concern regarding potential occupational exposures to the ultra-potent synthetic opioid carfentanil. However, little data are available on the toxicity of carfentanil in humans, particularly for dermal exposures. To begin to address this, permeation of carfentanil formulated in three vehicles, water, ethanol, and hand sanitizer was ...
Emily May, Lent, Kathleen J, Maistros, Jonathan M, Oyler   +2 more
openaire   +3 more sources

Pesticide Flow Analysis to Assess Human Exposure in Greenhouse Flower Production in Colombia [PDF]

, 2013
Human exposure assessment tools represent a means for understanding human exposure to pesticides in agricultural activities and managing possible health risks.
Camilo Lesmes-fabian, Binder, Claudia R., Claudia Binder, Lesmes-Fabian, Camilo, Claudia R. Binder   +4 more
core   +2 more sources

The mismeasure of dermal absorption [PDF]

Journal of Exposure Science & Environmental Epidemiology, 2010
The results of dermal absorption experiments are routinely and often exclusively reported in terms of fractional absorption. However, fractional absorption is not generally independent of skin loading conditions. As a consequence, experimental outcomes are commonly misinterpreted.
openaire   +2 more sources

The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]

, 2009
In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Korting, Hans Christian, Ackermann, K., Schäfer-Korting, Monika, Borgia, S. Lombardi, Mewes, K. R., S. Lombardi Borgia, M. Schäfer-Korting, K.R. Mewes, K. Ackermann, H.C. Korting   +9 more
core   +1 more source

Dermal absorption of testosterone in human and pig skin in vitro [PDF]

, 2018
The OECD test guideline 428 for the assessment of dermal absorption in vitro has been in force for more than a decade. Various sectors of industry utilise the method for the registration of chemical products.

core   +1 more source

Assessment of new scientific studies on human in vitro dermal absorption

EFSA Journal, 2015
This EFSA scientific report describes the results from the evaluation of new human in vitro studies on dermal absorption made available by European Crop Protection Association (ECPA) and the German public organisation Bundesinstitut für Risikobewertung ...
EFSA Working Group on Dermal Absorption
doaj   +1 more source

Variational finite element method to study the absorption rate of drug at various compartments through transdermal drug delivery system

Alexandria Journal of Medicine, 2015
Background: The delivery of drugs through dermal layers known as transdermal drug delivery is one of the important contributions in medical practice. It represents an alternative to oral drug delivery and is poised to provide a substitute to hypodermic ...
M.A. Khanday, Aasma Rafiq
doaj   +1 more source

Dermal Absorption of Sesquiterpene Lactones from Arnica Tincture

Pharmaceutics, 2022
Arnica tincture is a traditional herbal medicine used to treat blunt injuries, e.g., bruises and squeezes. In addition, a potential new use in the treatment of cutaneous leishmaniasis is currently under investigation.
Franziska M. Jürgens, Fabian C. Herrmann, Sara M. Robledo, Thomas J. Schmidt   +3 more
doaj   +1 more source