Results 21 to 30 of about 965,091 (147)
Cutaneous leishmaniasis (CL) is classified as a neglected tropical disease by the World Health Organization. As the standard drugs for the treatment of this disease suffer from severe unwanted effects, new effective and safe therapeutic options are ...
Franziska M. Jürgens +2 more
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Cosmetic products need to have a proven efficacy combined with a comprehensive toxicological assessment. Before the current Cosmetic regulation N°1223/2009, the 7th Amendment to the European Cosmetics Directive has banned animal testing for cosmetic ...
Manon Barthe +10 more
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Scientific Opinion on the Science behind the Revision of the Guidance Document on Dermal Absorption
This opinion provides the relevant data, evaluations and references that support the criteria proposed in the new draft guidance needed to facilitate assessment of dermal absorption of plant protection products (PPPs) under Directive 91/414/EEC[1] and ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
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Dermal (percutaneous, skin) absorption is a global term that describes the transport of chemicals from the outer surface of the skin both into the skin and into the systemic circulation. This Environmental Health Criteria document presents an overview of
Mangelsdorf, I. +2 more
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Pesticides must not pose unacceptable risks to human health, so risk assessments are conducted before products are authorised. Dermal exposure is often the main route of intake, so estimating realistic and trustworthy dermal absorption values is crucial ...
Christina Pieper +4 more
doaj +1 more source
Effective topical therapy of cutaneous fungal diseases requires the delivery of the active agent to the target site in adequate concentrations to produce a pharmacological effect and inhibit the growth of the pathogen.
Mahima Manian +3 more
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Firefighter occupational exposures were categorized as a class 1 (known) carcinogen by the International Agency for Research on Cancer in 2022. As a result, firefighters have become heavily focused on identifying effective and easy to implement ...
Chandler Probert +2 more
doaj +1 more source
m-phenylenediamine sulfate (mPDS) is used as an oxidative hair dye intermediate and is permitted in cosmetic products in Korea at concentrations up to 3%. However, quantitative data on its dermal absorption remain limited.
Han Nah Chung +5 more
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Dermal-related biological pathways associated with laser resurfacing kinetics.
Dermal-related biological pathways associated with laser resurfacing kinetics.
Deborah Finlay (11767619) +12 more
core +1 more source
Investigation of the solution chemistry and dermal absorption of novel copper (II) chelating agents that can serve as potential anti-inflammatory drugs [PDF]
This study describes the investigation of the solution chemistry of the copper (II) complexes of homopiperazine and an adamentane derivative of homopiperazine (PCU.homo) using glass electrode potentiometry, UV/VIS spectroscopy, speciation modeling ...
Mokalane, Kagiso
core +1 more source

