Results 21 to 30 of about 965,091 (147)

Evaluation of Pharmacokinetic and Toxicological Parameters of Arnica Tincture after Dermal Application In Vivo

open access: yesPharmaceutics, 2022
Cutaneous leishmaniasis (CL) is classified as a neglected tropical disease by the World Health Organization. As the standard drugs for the treatment of this disease suffer from severe unwanted effects, new effective and safe therapeutic options are ...
Franziska M. Jürgens   +2 more
doaj   +1 more source

Safety Testing of Cosmetic Products: Overview of Established Methods and New Approach Methodologies (NAMs)

open access: yesCosmetics, 2021
Cosmetic products need to have a proven efficacy combined with a comprehensive toxicological assessment. Before the current Cosmetic regulation N°1223/2009, the 7th Amendment to the European Cosmetics Directive has banned animal testing for cosmetic ...
Manon Barthe   +10 more
doaj   +1 more source

Scientific Opinion on the Science behind the Revision of the Guidance Document on Dermal Absorption

open access: yesEFSA Journal, 2011
This opinion provides the relevant data, evaluations and references that support the criteria proposed in the new draft guidance needed to facilitate assessment of dermal absorption of plant protection products (PPPs) under Directive 91/414/EEC[1] and ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
doaj   +1 more source

Dermal absorption

open access: yes, 2022
Dermal (percutaneous, skin) absorption is a global term that describes the transport of chemicals from the outer surface of the skin both into the skin and into the systemic circulation. This Environmental Health Criteria document presents an overview of
Mangelsdorf, I.   +2 more
core   +1 more source

In Vitro Human Dermal Absorption Studies on Pesticides in Complex Mixtures: Investigation of Guidance Criteria and Possible Impact Parameters

open access: yesToxics
Pesticides must not pose unacceptable risks to human health, so risk assessments are conducted before products are authorised. Dermal exposure is often the main route of intake, so estimating realistic and trustworthy dermal absorption values is crucial ...
Christina Pieper   +4 more
doaj   +1 more source

Investigation of the Dermal Absorption and Irritation Potential of Sertaconazole Nitrate Anhydrous Gel

open access: yesPharmaceutics, 2016
Effective topical therapy of cutaneous fungal diseases requires the delivery of the active agent to the target site in adequate concentrations to produce a pharmacological effect and inhibit the growth of the pathogen.
Mahima Manian   +3 more
doaj   +1 more source

Impact of Skin Decontamination Wipe Solutions on the Percutaneous Absorption of Polycyclic Aromatic Hydrocarbons

open access: yesToxics
Firefighter occupational exposures were categorized as a class 1 (known) carcinogen by the International Agency for Research on Cancer in 2022. As a result, firefighters have become heavily focused on identifying effective and easy to implement ...
Chandler Probert   +2 more
doaj   +1 more source

In Vitro Dermal Absorption of m-Phenylenediamine Sulfate in Mini-Pig Skin Using LC–MS/MS Quantification

open access: yesSci
m-phenylenediamine sulfate (mPDS) is used as an oxidative hair dye intermediate and is permitted in cosmetic products in Korea at concentrations up to 3%. However, quantitative data on its dermal absorption remain limited.
Han Nah Chung   +5 more
doaj   +1 more source

Dermal-related biological pathways associated with laser resurfacing kinetics.

open access: yes, 2021
Dermal-related biological pathways associated with laser resurfacing kinetics.
Deborah Finlay (11767619)   +12 more
core   +1 more source

Investigation of the solution chemistry and dermal absorption of novel copper (II) chelating agents that can serve as potential anti-inflammatory drugs [PDF]

open access: yes, 2011
This study describes the investigation of the solution chemistry of the copper (II) complexes of homopiperazine and an adamentane derivative of homopiperazine (PCU.homo) using glass electrode potentiometry, UV/VIS spectroscopy, speciation modeling ...
Mokalane, Kagiso
core   +1 more source

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