Results 41 to 50 of about 965,091 (147)

Verification of P-Glycoprotein Function at the Dermal Barrier in Diffusion Cells and Dynamic “Skin-On-A-Chip” Microfluidic Device

open access: yesPharmaceutics, 2020
The efficacy of transdermal absorption of drugs and the irritation or corrosion potential of topically applied formulations are important areas of investigation in pharmaceutical, military and cosmetic research.
Ágnes Bajza   +8 more
doaj   +1 more source

Hair follicle dermal cells: a morphological, behavioural and molecular study [PDF]

open access: yes, 1995
Anatomy and smooth muscle a-actin expression in hair follicles from a variety of animal species (Mink, Polecat, Meerkat, Grey squirrel and stoat) was investigated. Smooth muscle ɑ-actin expression was related to follicle activity. Expression was greatest
Sleeman, Matthew Alexander, Sleeman, M
core  

Human in vitro dermal absorption PPPs dataset

open access: yes, 2019
<p>Combined ECPA and BfR dataset of human in vitro dermal absorption studies conducted with Plant Protection Products (PPPs).</p> <p>The published dataset has been evaluated for the update of the EFSA Guidance on Dermal Absorption.< ...
European Food Safety Authority (5023532)   +1 more
core   +1 more source

Primary dermal melanoma in a patient with a history of multiple malignancies: a case report with molecular characterization [PDF]

open access: yes, 2013
Introduction: Primary dermal melanoma (PDM) is a recently described clinical entity accounting for less than 1% of all melanomas. Histologically, it is located in the dermis or subcutaneous tissue, and it shows no connections with the overlying epidermis.
Palomba, Grazia   +19 more
core   +1 more source

Dermal Absorption and Quantitative Analysis of Amaranth, a Cosmetic Colorant, in Rat Skin Using an In Vitro Franz Diffusion Model

open access: yesCosmetics
Amaranth (R2) is used as a color additive in cosmetics. In Korea, R2 is permitted only as a cosmetic colorant and is prohibited in products intended for infants and children under 13 years of age; in Europe, it is regulated solely as a cosmetic colorant ...
Jung Dae Lee   +3 more
doaj   +1 more source

Absorption and excretion of Tetrabromobisphenol A in male Wistar rats following subchronic dermal exposure

open access: yes, 2016
Tetrabromobisphenol A (TBBPA) is widely used as a flame retardant and frequently detected in environmental and biological samples. In this study, male Wistar rats were repeatedly exposed by dermal application to 20, 60, 200 and 600 mg TBBPA/kg body ...
Li, Liangzhong   +7 more
core   +1 more source

Percutaneous Absorption of Fireground Contaminants: Naphthalene, Phenanthrene, and Benzo[a]pyrene in Porcine Skin in an Artificial Sweat Vehicle

open access: yesToxics
Firefighters face significant risks of exposure to toxic chemicals, such as polycyclic aromatic hydrocarbons (PAHs), during fire suppression activities.
Chandler Probert   +3 more
doaj   +1 more source

Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases

open access: yesJournal of Occupational Medicine and Toxicology, 2006
There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals.
Angerer Jürgen   +3 more
doaj   +1 more source

P24-07 Proposal for revision of default dermal absorption values in regulatory toxicology

open access: yes
The German Federal Institute for Risk Assessment (BfR) compiled an updated data set of dermal absorption studies for pesticides - the BfR data set 2024. The data set includes studies conducted up to 2024.
Marx-Stoelting, P.   +3 more
core   +1 more source

Skin Permeability of Perfluorocarboxylic Acids Using Flow-Through Diffusion on Porcine Skin

open access: yesToxics
Per- and polyfluoroalkyl substances (PFAS) are found in a variety of places including cosmetics, rain jackets, dust, and water. PFAS have also been applied to occupational gear to protect against water and oils.
Andrew Stephen Hall   +4 more
doaj   +1 more source

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