Results 31 to 40 of about 1,062,941 (282)
Investigation of the solution chemistry and dermal absorption of novel copper (II) chelating agents that can serve as potential anti-inflammatory drugs [PDF]
, 2011 This study describes the investigation of the solution chemistry of the copper (II) complexes of homopiperazine and an adamentane derivative of homopiperazine (PCU.homo) using glass electrode potentiometry, UV/VIS spectroscopy, speciation modeling ...
Mokalane, Kagiso
core +1 more source
Cosmetics, 2021 Cosmetic products need to have a proven efficacy combined with a comprehensive toxicological assessment. Before the current Cosmetic regulation N°1223/2009, the 7th Amendment to the European Cosmetics Directive has banned animal testing for cosmetic ...
Manon Barthe +10 more
doaj +1 more source
, 2022 Dermal (percutaneous, skin) absorption is a global term that describes the transport of chemicals from the outer surface of the skin both into the skin and into the systemic circulation. This Environmental Health Criteria document presents an overview of
Mangelsdorf, I. +2 more
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Human in vitro dermal absorption PPPs dataset
, 2019 <p>Combined ECPA and BfR dataset of human in vitro dermal absorption studies conducted with Plant Protection Products (PPPs).</p> <p>The published dataset has been evaluated for the update of the EFSA Guidance on Dermal Absorption.< ...
European Food Safety Authority (5023532) +1 more
core +1 more source
, 2010 Contains fulltext : 89678.pdf (Publisher’s version ) (Closed access)Most QSARs for dermal absorption predict the permeability coefficient, K(p), of a molecule, which is valid for infinite dose conditions.
Buist, H.E. +9 more
core +2 more sources
ToxicsFirefighter occupational exposures were categorized as a class 1 (known) carcinogen by the International Agency for Research on Cancer in 2022. As a result, firefighters have become heavily focused on identifying effective and easy to implement ...
Chandler Probert +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dermal Absorption of Inorganic Arsenic from Water
, 2003 This white paper explores questions of the potential for exposure to inorganic arsenic in water through dermal contact when providing guidance about treatment options to private well owners.
Post, Gloria
core +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Applicability of in silico tools for the prediction of dermal absorption for pesticides [PDF]
, 2018 Based on the “Human in vitro dermal absorption datasets” published as supporting information to the revised EFSA Guidance on Dermal Absorption, in silico models for prediction of absorption across the skin have been evaluated.
Charistou, Agathi +13 more
core +1 more source