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Skin absorption in vitro of glycol ethers

International Archives of Occupational and Environmental Health, 1999
The increased use of glycol ethers (GEs) for water-based paints and cleaning products, combined with a lack of information about many of these products, particularly with regard to the effects of percutaneous exposure, led us to evaluate the skin absorption rates of a group of glycol ethers in vitro.Skin permeation was calculated using the Franz cell ...
LARESE FILON, FRANCESCA   +6 more
openaire   +3 more sources

Skin barrier function for regulatory skin absorption tests and effects on testosterone and sucrose absorption

Toxicology in Vitro
In vitro absorption through human skin is a critical component in the safety assessment of chemicals, crop protection products, consumer healthcare products and cosmetics. A barrier integrity assay is used to identify skin samples which are potentially damaged.
Thomas, Brackin   +4 more
openaire   +2 more sources

Percutaneous absorption of water in skin: a review

Reviews on Environmental Health, 2014
Abstract Background: The stratum corneum has a wide variety of important functions, including host protection from foreign chemicals and bacteria, water loss prevention, and body temperature regulation. While water absorption studies on healthy intact skin are abundant, data on the percutaneous absorption of water in ...
Collin M, Blattner   +3 more
openaire   +2 more sources

Absorption of hexavalent chromium by skin in man

Archives of Toxicology, 1981
Absorption by skin of hexavalent chromium from aqueous solutions of sodium chromate in man was investigated. It was found that the amount of chromium absorbed was related to the concentration of Cr6+ in solution and to time of exposure. For 0.01, 0.1, and 0.2 molar solutions of chromium, skin absorption rates during 1 h exposure were 1.1, 6.5, and 10.0
openaire   +2 more sources

Percutaneous absorption in diseased skin: an overview

Journal of Applied Toxicology, 2012
ABSTRACTThe stratum corneum's (SC) functions include protection from external hazardous environments, prevention of water loss and regulation of body temperature. While intact skin absorption studies are abundant, studies on compromised skin permeability are less common, although products are often used to treat affected skin. We reviewed literature on
Audris, Chiang   +2 more
openaire   +2 more sources

[Skin absorption promotors].

Annales pharmaceutiques francaises, 1993
Transdermal penetration of drugs is currently much studied because it presents several attractive aspects, avoiding first past effects and offering means of immediate breaking of the therapeutic in case of hitch. But it must overcome the very efficient hindrance of the epidermal barrier.
C, Durandeau   +3 more
openaire   +1 more source

Absorption of materials by or through the living skin

International Journal of Cosmetic Science, 1985
SynopsisThe skin comes into contact with a large range of materials either deliberately or inadvertently. It should be possible to predict the exact transport rates of these materials through the skin as a function of the physicochemical properties of the different compounds.
openaire   +2 more sources

Skin absorption enhancers.

Critical reviews in therapeutic drug carrier systems, 1993
When we try to maximize drug flux through the skin, we usually meet major difficulties because of the impervious nature of the stratum corneum. A popular solution incorporates penetration enhancers into transdermal products. Such materials ideally possess the sole property of reversibly reducing the barrier resistance of the horny layer, allowing the ...
A C, Williams, B W, Barry
openaire   +1 more source

SKIN ABSORPTION OF LEAD

The Lancet, 1988
T M, Florence, S G, Lilley, J L, Stauber
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Paraquat Poisoning by Skin Absorption: A Review

Human Toxicology, 1988
All reported cases of paraquat poisoning by absorption through the skin are briefly reviewed. It is concluded that, while paraquat cannot be absorbed significantly through intact human skin, damage to the skin, either by paraquat itself or by other means, will permit greater systemic absorption and possibly poisoning.
openaire   +2 more sources

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