Results 251 to 260 of about 495,232 (306)
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Annales pharmaceutiques francaises, 1993
Transdermal penetration of drugs is currently much studied because it presents several attractive aspects, avoiding first past effects and offering means of immediate breaking of the therapeutic in case of hitch. But it must overcome the very efficient hindrance of the epidermal barrier.
C, Durandeau +3 more
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Transdermal penetration of drugs is currently much studied because it presents several attractive aspects, avoiding first past effects and offering means of immediate breaking of the therapeutic in case of hitch. But it must overcome the very efficient hindrance of the epidermal barrier.
C, Durandeau +3 more
openaire +1 more source
Glyphosate Skin Binding, Absorption, Residual Tissue Distribution, and Skin Decontamination
Toxicological Sciences, 1991Glyphosate is a broad-spectrum postemergence translocated herbicide. Its interactions with skin and potential systemic availability through percutaneous absorption was studied by skin binding, skin absorption, residual tissue distribution, and skin decontamination.
R C, Wester +4 more
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Critical reviews in therapeutic drug carrier systems, 1993
When we try to maximize drug flux through the skin, we usually meet major difficulties because of the impervious nature of the stratum corneum. A popular solution incorporates penetration enhancers into transdermal products. Such materials ideally possess the sole property of reversibly reducing the barrier resistance of the horny layer, allowing the ...
A C, Williams, B W, Barry
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When we try to maximize drug flux through the skin, we usually meet major difficulties because of the impervious nature of the stratum corneum. A popular solution incorporates penetration enhancers into transdermal products. Such materials ideally possess the sole property of reversibly reducing the barrier resistance of the horny layer, allowing the ...
A C, Williams, B W, Barry
openaire +1 more source
Fatal paraquat poisonings after skin absorption
Medical Journal of Australia, 1982This paper reports five cases of fatal paraquat poisoning after skin absorption in adult Papua New Guinea men. Three incidents followed occupational accidents, one victim used paraquat concentrate to treat a scabies infestation, and one used it to treat head lice. All had marked blistering and excoriation, and all died from respiratory failure.
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Models for Skin Absorption and Skin Toxicity Testing
2007This chapter includes information about models for skin absorption testing and skin toxicity testing in a condensed form. At first, the structure and function of human skin is described discussing the contribution of the different skin layers and skin appendages to skin absorption. Moreover, various skin absorption pathways are discussed.
Ulrich F. Schaefer +4 more
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Toxicology in Vitro
In vitro absorption through human skin is a critical component in the safety assessment of chemicals, crop protection products, consumer healthcare products and cosmetics. A barrier integrity assay is used to identify skin samples which are potentially damaged.
Thomas, Brackin +4 more
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In vitro absorption through human skin is a critical component in the safety assessment of chemicals, crop protection products, consumer healthcare products and cosmetics. A barrier integrity assay is used to identify skin samples which are potentially damaged.
Thomas, Brackin +4 more
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Basic Mathematics in Skin Absorption
2017Frequently, analysis of skin absorption does not only require the careful evaluation of experimental data but also the fundamental understanding of underlying physics to apply the appropriate mathematical concepts to attain insight into transport kinetics. This chapter will introduce the basic mathematics which are necessary to evaluate skin permeation
Dominik Selzer +3 more
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Mathematical characterization of skin absorption
2016Work on the mathematical modeling and data analysis of skin absorption with focus on finite dosing is presented within this thesis. It could be shown that correction of experimental data based on the area of application should be taken into consideration depending on the drug's lipophilic character.
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