Results 81 to 90 of about 492,394 (350)

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

open access: yesAdvanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong   +3 more
wiley   +1 more source

Solute–Vehicle–Skin Interactions and Their Contribution to Pharmacokinetics of Skin Delivery

open access: yesPharmaceutics
Human skin provides an effective route of delivery for selected drugs. Topical penetration of molecules is largely attributed to passive diffusion, and the degree of penetration can be represented by in silico, in vitro, and ex vivo models.
Pronalis Tapfumaneyi   +6 more
doaj   +1 more source

Transdermal evaluation of caffeine in different formulations and excipients [PDF]

open access: yes, 2013
Background: The stratum corneum(SC) forms adifficultphysical barrier fordrugs to pass through the skin. Several strategieswere developed to overcome this barrier.Optimization of topical drug formulations by selected excipients may facilitate the ...
Boonen, Jente   +7 more
core   +2 more sources

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro   +7 more
wiley   +1 more source

Lattice Boltzmann model of percutaneous drug absorption

open access: yesTheoretical and Applied Mechanics Letters, 2019
A lattice Boltzmann numerical modeling method was developed to predict skin concentration after topical application of a drug on the skin. The method is based on D2Q9 lattice spaces associated with the Bhatnagar-Gross-Krook (BGK) collision term to solve ...
Arman Safdari, Kyung Chun Kim
doaj   +1 more source

Verification of P-Glycoprotein Function at the Dermal Barrier in Diffusion Cells and Dynamic “Skin-On-A-Chip” Microfluidic Device

open access: yesPharmaceutics, 2020
The efficacy of transdermal absorption of drugs and the irritation or corrosion potential of topically applied formulations are important areas of investigation in pharmaceutical, military and cosmetic research.
Ágnes Bajza   +8 more
doaj   +1 more source

A two-phase two-layer model for transdermal drug delivery and percutaneous absorption

open access: yes, 2014
One of the promising frontiers of bioengineering is the controlled release of a therapeuticdrug from a vehicle across the skin (transdermal drug delivery).
de Monte, Filippo, Pontrelli, Giuseppe
core   +1 more source

Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]

open access: yes, 2019
© 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria   +5 more
core   +2 more sources

Kinetic Insights into Precursor‐Assisted Soft Sphere Close Packing Revealed by In Situ GISAXS with Implications for Gas Sensing

open access: yesAdvanced Functional Materials, EarlyView.
The versatile precursor‐assisted soft sphere close packing during slot‐die coating is investigated with in situ X‐ray scattering. The soft crystallization pathways towards a close packing involve multistep structural transitions such as surface nucleation, in‐plane, and out‐of‐plane crystallization.
Guangjiu Pan   +14 more
wiley   +1 more source

Skin models for the testing of transdermal drugs

open access: yesClinical Pharmacology: Advances and Applications, 2016
Eman Abd,1 Shereen A Yousef,1 Michael N Pastore,2 Krishna Telaprolu,1 Yousuf H Mohammed,1 Sarika Namjoshi,1 Jeffrey E Grice,1 Michael S Roberts1,2 1Translational Research Institute, School of Medicine, University of Queensland, Brisbane, 2School of ...
Abd E   +7 more
doaj  

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