Results 61 to 70 of about 5,531,096 (302)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A review of skin cancer primary prevention activities in primary care settings

Public Health Research & Practice
Objectives: Skin cancer is highly preventable through primary prevention activities such as avoiding ultraviolet radiation exposure during peak times and regular use of sun protection.
Nehal Singh , Kate LA Dunlop , Nikki Woolley, Tracey Wills Vashishtha , Diona L Damian, Kylie Vuong, Anne E Cust , Amelia K Smit   +7 more
doaj   +1 more source

Preventative therapies for healthy women at high risk of breast cancer [PDF]

, 2014
Ivana Sestak Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, UKAbstract: Tamoxifen has been shown to reduce the risk of developing estrogen receptor (ER)-positive ...
Sestak I, Sestak, I
core   +1 more source

Primary prevention of skin cancer in primary care settings - A scoping review

, 2022
Background: Skin cancer is highly preventable through primary prevention activities such as avoiding UV exposure during peak times and regular use of sun protection.
Dunlop, Kate, Singh, Nehal, Smit, Amelia K, Woolley, Nikki, Cust, Anne E, Damien, Diona L, Vuong, Kylie   +6 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

mHealth Approaches in Managing Skin Cancer: Systematic Review of Evidence-Based Research Using Integrative Mapping

JMIR mHealth and uHealth, 2018
BackgroundmHealth, which encompasses mobile health technologies and interventions, is rapidly evolving in various medical specialties, and its impact is evident in oncology. In particular, mHealth has established itself as a prominent part of dermatology
Choi, Jihye, Cho, Youngtae, Woo, Hyekyung   +2 more
doaj   +1 more source

Skin cancer prevention progress report 2015 [PDF]

Skin cancer is the most commonly diagnosed cancer in the United States, yet most cases are preventable. Every year in the United States, nearly 5 million people are treated for skin cancer, at an estimated cost of $8.1 billion.

core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Primary prevention of skin cancer in patients after kidney transplantation – a literature review

Cancer Treatment and Research Communications
Renal transplant recipients (RTRs) require long-term immunosuppression, which contributes to the increased incidence of skin cancer. The purpose of this literature review is to present interventions aimed at preventing skin cancer in RTRs.
Malwina Nowogrodzka, Alicja Dębska-Ślizień, Andrzej Chamienia, Beata Imko-Walczuk   +3 more
doaj   +1 more source

Associations between linguistic acculturation and skin cancer knowledge and beliefs among U.S. Hispanic adults

Preventive Medicine Reports, 2019
The incidence of melanoma among U.S. Hispanics is rising and Hispanics have poorer melanoma survival compared to non-Hispanic whites. Acculturation has been linked with skin cancer-related behaviors among Hispanic individuals, such that Hispanic ...
Adrienne S. Viola, Jerod L. Stapleton, Elliot J. Coups   +2 more
doaj   +1 more source