Results 51 to 60 of about 5,213,049 (300)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Global controversies and advances in skin cancer

, 2013
Advances and controversies of skin cancer prevention in the Asian-Pacific region are to be examined in the world's first Global Controversies and Advances in Skin Cancer Conference to be held in Brisbane, Australia this November.
Dunn, Jeff, Baldwin, Louise
core   +1 more source

National Skin Cancer Prevention Plan 2023-2026

, 2023
The National Cancer Strategy 2017-20261 aims to reduce the cancer burden in Ireland. Cancer prevention is a cornerstone of the National Cancer Strategy as it offers the most cost-effective, long-term approach for cancer control.
National Cancer Control Programme
core  

‘I am not someone who gets skin cancer’: Risk, time and malignant melanoma [PDF]

, 2013
‘Delay’ is a term used in the cancer literature since the 1930s to describe the period between self-detection of a concerning sign of possible disease and presentation to a health professional.
Heyman, Bob, Topping, Annie, Topping, A.; id_orcid, Nkosana-Nyawata, I., Nkosana-Nyawata, Idah, Heyman, B.   +5 more
core   +1 more source

Incongruence between Physician, Patient, and Medical Chart Report of Skin Cancer Prevention Counseling

, 2022
Skin cancer incidence in the United States has risen rapidly in recent decades, underscoring the need for accessible and effective prevention practices.
Weinstock, Martin A., Martin A. Weinstock, Natalie H. Matthews, Matthews, Natalie H., Augustine W. Kang, Patricia Markham Risica, Kang, Augustine W., Risica, Patricia Markham   +7 more
core   +1 more source

Epigenetic Cancer Prevention Mechanisms in Skin Cancer [PDF]

The AAPS Journal, 2013
Epigenetics is an important emerging area for study of mechanisms of cancer prevention. In recent years, it has been realized that cancer prevention agents, derived from natural dietary sources, impact cancer cell survival by modulating epigenetic processes.
Kamalika, Saha, Thomas J, Hornyak, Richard L, Eckert   +2 more
openaire   +2 more sources

The seroepidemiology of human-papillomavirus in relation to non-melanoma skin cancer [PDF]

, 2009
PhDNon-melanoma skin cancer, comprising basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) is the most commonly diagnosed cancer in Caucasian populations.
Casabonne, Delphine
core   +4 more sources

Effect of the Interaction Between Selenium and Zinc on DNA Repair in Association With Cancer Prevention

, 2019
Tanriverdi, Ozgur/0000-0002-0598-7284; Yildiz, Aysegul/0000-0001-6356-7459WOS: 000489249900002PubMed ID: 31624720Cancer is the most common cause of death worldwide. Annually, more than ten million new cancer cases are diagnosed, and more than six million
Tanrıverdi, Özgür, Yildiz, Aysegul, Kaya, Yesim   +2 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source