Results 171 to 180 of about 5,213,049 (300)

Skin Cancer Prevention across the G7, Australia and New Zealand: A Review of Legislation and Guidelines. [PDF]

Curr Oncol, 2023
Conte S, Aldien AS, Jetté S, LeBeau J, Alli S, Netchiporouk E, Lagacé F, Lefrançois P, Iannattone L, Litvinov IV.   +9 more
europepmc   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

Reasons for Indoor and Outdoor Tanning: Starting Points for Skin Cancer Prevention Based on a Nationwide Study. [PDF]

Curr Oncol
Diehl K, Voß L, Breitbart EW, Hübner IM, Görig T.   +4 more
europepmc   +1 more source

Eating Habits, Knowledge about Cancer Prevention and the HPLP Scale in Turkish Adolescents

, 2008
Background: Nutritional status and healthy lifestyle are important factors not only in cancer etiology but also for prevention efforts. A good nutritional status contributes to a healthy life with high economic, social and cultural level.
Otles, Semih, Ceber, Esin, Saydam, Birsen Karaca, Ozenturk, Gulsun, Can, Hafize Ozturk, Sogukpinar, Neriman   +5 more
core  

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

The Surgeon General\ue2\u20ac\u2122s call to action to prevent skin cancer

This document is a Call to Action to partners in prevention from various sectors across the nation to address skin cancer as a major public health problem.

core  

Skin cancer prevention: knowledge and perceptions of a nationwide sample of youth. [PDF]

Ann Fam Med, 2022
Strome A, Chang T, Waselewski M, Lamberg O, Herbert K.   +4 more
europepmc   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu, Ziliang Nie, Xi Chen, Guangyu Ji, Yajing Zhang, Zhiqun Zhao, Yuhong Zhang, Xinlong Du, Zhenzhen Zhou, Jiayi Li, Yaozong Yang, Fengqi Sun, Zhibo Yan, Haiquan Lu   +13 more
wiley   +1 more source

ChatGPT-Generated Advice on Sun Protection and Skin Cancer Prevention Compared to American Academy of Dermatology Guidelines: Cross-Sectional Content Analysis. [PDF]

JMIR Dermatol
Qeyam H, Al-Rusan A.
europepmc   +1 more source

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source