Results 151 to 160 of about 158,088 (302)

Nanoparticles as a Therapeutic Delivery System for Skin Cancer Prevention and Treatment. [PDF]

JID Innov, 2023
Chang J, Yu B, Saltzman WM, Girardi M.
europepmc   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

The role of community pharmacists in primary and secondary prevention of skin cancer: an evaluation of a Flemish skin cancer prevention campaign. [PDF]

BMC Public Health, 2023
Proesmans K, Van Vaerenbergh F, Lahousse L.   +2 more
europepmc   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, EarlyView.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source

Multimodal Transplant-clinic-based Skin Cancer Prevention Education for Organ Transplant Recipients: Feasibility Study. [PDF]

Transplant Direct, 2023
Yu R, Miura K, Chambers DC, Hopkins PM, Proby CM, Bibee K, Plasmeijer EI, Green AC.   +7 more
europepmc   +1 more source

Analysis of the Relationships between Esophageal Cancer Cases and Climatic Factors Using a Geographic Information System (GIS): a Case Study of Ardabil province in Iran [PDF]

Esophageal cancer is a mjaor health problems in many parts of the world. A geographical information system (GIS) allows investigation of the geographical distribution of diseases. The purpose of the present study was to explore the relationship between
صادقیه اهری, سعید, امانی, فیروز, بابایی اقدم, فریدون, اخگری, لیلا, یزدانبد, عباس   +4 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Risk factors for thick melanoma and for melanoma death:Implications for skin cancer screening

EJC Skin Cancer
L. Brochez, P. Autier
doaj   +1 more source

Skin Cancer Prevention and Antiaging: Role of Nicotinamide. [PDF]

Int J Mol Sci
Moro F, Panebianco ASI, Bartolocci V, Capone A, Di Guardo A, Hyeraci M, Gemma GPA, Di Lella G, Colonna L, Ricci F, Dellambra E, Fania L.   +11 more
europepmc   +1 more source

Skin Cancer Prevention across the G7, Australia and New Zealand: A Review of Legislation and Guidelines. [PDF]

Curr Oncol, 2023
Conte S, Aldien AS, Jetté S, LeBeau J, Alli S, Netchiporouk E, Lagacé F, Lefrançois P, Iannattone L, Litvinov IV.   +9 more
europepmc   +1 more source