Results 41 to 50 of about 5,050,584 (299)

Economic aspects of skin cancer management in Eastern Croatia

Journal of Health Sciences, 2015
Introduction: In the past several decades there has been a substantial increase in the incidence of skin cancers worldwide and Croatia is no exception.
Ivan Miškulin, Želimir Orkić, Maja Miškulin   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Interest in Skin Cancer in Urban Populations: A Retrospective Analysis of Google Search Terms in Nine Large German Cities

Acta Dermato-Venereologica, 2019
Skin cancer is a major public health issue, which could be reduced through prevention programmes. How­ever, prevention utilization is not very prevalent. It is therefore important to understand individuals’ interest in skin cancer. Google AdWords Keyword
Linda Tizek, Maximilian C. Schielein, Melvin Rüth, Rolf-Markus Szeimies, Wolfgang G. Philipp-Dormston, Stephan A. Braun, Christine Hecker, Bernadette Eberlein, Tilo Biedermann, Alexander Zink   +9 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

MEDICAL AND SOCIAL REASONING FOR IMPROVING THE ORGANISATION OF PREVENTING AND FIGHTING SKIN CANCER IN THE CONDITIONS OF THE PUBLIC HEALTH SYSTEM DEVELOPMENT

Клінічна та профілактична медицина, 2023
Introduction. Scientific reasoning for improving the organisation of cancer prevention and the providing onco-dermatological care to the population in the conditions of the public health system development. Materials and methods.
Nataliia M. Kalashnykova, Tetiana S. Gruzieva   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Skin cancer has a large impact on our public hospitals but prevention programs continue to demonstrate strong economic credentials

Australian and New Zealand Journal of Public Health, 2017
Objectives: While skin cancer is still the most common cancer in Australia, important information gaps remain. This paper addresses two gaps: i) the cost impact on public hospitals; and ii) an up‐to‐date assessment of economic credentials for prevention.
Sophy T.F. Shih, Rob Carter, Sue Heward, Craig Sinclair   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Evaluation of the National Skin Cancer Campaign: a Swiss experience of Euromelanoma

Swiss Medical Weekly, 2017
AIMS OF THE STUDY Skin cancer is a burden to healthcare and patients worldwide. The incidence of skin cancer has been rising during recent decades and this trend is expected to continue in the future.
Sven Lieberherr, S. Morteza Seyed Jafari, Simone Cazzaniga, Enrica Bianchi, Bettina Schlagenhauff, Gion Tscharner, Jürg Hafner, Carlo Mainetti, Anne-Karine Lapointe, Robert E. Hunger   +9 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source