Results 31 to 40 of about 12,136 (214)

Oxyresveratrol suppressed melanogenesis, dendrite formation, and melanosome transport in melanocytes via regulation of the MC1R/cAMP/MITF pathway

open access: yesScientific Reports
Oxyresveratrol, a natural derivative of resveratrol, has been shown to possess antimelanogenic properties. However, the underlying mechanism and its effect on melanin transfer remain poorly understood.
Jianhua Zhang   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A retrospective real-world analysis of placental-based allografts on pressure ulcers

open access: yesSAGE Open Medicine
Objective: The records from a network of mobile wound clinics were analyzed to evaluate the efficacy of a human placental-based allograft compared with the standard of care for patients with chronic pressure ulcer wounds and multiple comorbidities ...
David Kay   +2 more
doaj   +1 more source

Evolving clonal nevus—case report with serial digital dermatoscopy and dermatopathology

open access: yesDermatology Practical & Conceptual, 2015
We present a case of a clonal nevus arising from a previously banal melanocytic nevus over a 15-month period on the central back of a 30-year-old woman in a primary care skin cancer practice in Melbourne, Australia.
Mike Inskip, Jill Magee
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Microcystic adnexal carcinoma of the cheek—a case report with dermatoscopy and dermatopathology

open access: yesDermatology Practical & Conceptual, 2015
We present a case report of a microcystic adnexal carcinoma on the cheek of a 67-year-old man. Clinical, dermatoscopic and dermatopathologic images are presented.
Mike Inskip, Jill Magee
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Pathogenesis of Chronic Urticaria: An Overview

open access: yesDermatology Research and Practice, 2014
The pathogenesis of chronic urticaria is not well delineated and the treatment is palliative as it is not tied to the pathomechanism. The centrality of mast cells and their inappropriate activation and degranulation as the key pathophysiological event ...
Sanjiv Jain
doaj   +1 more source

Trending Anti-Aging Peptides

open access: yesCosmetics, 2020
The development of synthetic peptides for skin care dates to the 1980s. The cosmetic industry periodically launches new peptides, as they are promising and appealing active ingredients in the growing and innovative cosmetics market. In this study, trends
Marta Salvador Ferreira   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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