Results 41 to 50 of about 12,136 (214)

Protective Effects of Salicornia europaea on UVB-Induced Misoriented Cell Divisions in Skin Epithelium

Cosmetics, 2020
Correct orientation of cell division is extremely important in the maintenance, regeneration, and repair of continuously proliferating tissues, such as the epidermis.
Natsumi Doi, Hiro Togari, Kenji Minagi, Koichi Nakaoji, Kazuhiko Hamada, Masaaki Tatsuka   +5 more
doaj   +1 more source

Facial Treatment with 3-O-Cetyl Ascorbic Acid for Improvement of Skin Texture: Uptake, Effectiveness, and In Vitro Carcinogenicity Assessment

Cosmetics, 2021
Ascorbic acid (AA) is a water-soluble vitamin that is found at high concentrations in normal skin. The important and well-known benefits of using AA in skin health include the stimulation of collagen synthesis and the assistance of protection against ...
Natsumi Doi, Yoshifumi Yamada, Misaki Toyoshima, Yuki Kondo, Koichi Nakaoji, Kazuhiko Hamada, Masaaki Tatsuka   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Olea europea and By-Products: Extraction Methods and Cosmetic Applications

Cosmetics, 2023
Currently, in addition to the use of olive oil in cosmetics, the use of olive-derived bioactives and their incorporation into cosmetics is a growing trend.
Cecilia Dauber, Emma Parente, María Pía Zucca, Adriana Gámbaro, Ignacio Vieitez   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A Case of Pityriasis Lichenoides Chronica Successfully Treated With Upadacitinib

Case Reports in Dermatological Medicine
Pityriasis lichenoides chronica (PLC) is a chronic cutaneous disorder of unknown cause that is thought to be a proliferation of T-cells in response to an antigen or infection. We introduce a case of a 62-year-old female who presented with an erythematous
Olivia R. Noble, David J. Cohen, Lynn Cooper   +2 more
doaj   +1 more source

Gardeniae Fructus Enhances Skin Barrier Function via AHR-Mediated FLG/LOR/IVL Expression

Molecules
Gardeniae Fructus (GF), a traditional Chinese medicine rich in iridoids, has demonstrated skin-improving effects. However, its mechanisms for enhancing epidermal barrier function remain unclear.
Kaile Zong, Fangni Zhou, Kewei Xu, Junzi Dong, Qing Huang, Jianxin Wu   +5 more
doaj   +1 more source

Improvement of Human Epidermal Barrier Structure and Lipid Profile in Xerotic- and Atopic-Prone Skin via Application of a Plant-Oil and Urea Containing pH 4.5 Emulsion

Cosmetics, 2023
Epidermal barrier dysfunction can lead to xerotic skin and promote skin disorders like atopic dermatitis. Atopic skin is characterized by reduced water-retaining compounds, altered lipid composition and elevated skin pH.
Jürgen Blaak, Dorothee Dähnhardt, Stephan Bielfeldt, Christiane Theiss, Isabel Simon, Klaus-Peter Wilhelm, Stephan Dähnhardt-Pfeiffer, Peter Staib   +7 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Measurement of Stress Relief during Scented Cosmetic Product Application Using a Mood Questionnaire, Stress Hormone Levels and Brain Activation

Cosmetics, 2022
Nowadays, consumers’ well-being plays a decisive role in the purchase of cosmetic products. Although factors influencing consumers’ well-being are very subjective, companies strive to develop their products in such a way that a positive effect is likely.
Arielle Springer, Laura Höckmeier, Doris Schicker, Stefan Hettwer, Jessica Freiherr   +4 more
doaj   +1 more source