Results 41 to 50 of about 5,615,778 (256)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Olea europea and By-Products: Extraction Methods and Cosmetic Applications

Cosmetics, 2023
Currently, in addition to the use of olive oil in cosmetics, the use of olive-derived bioactives and their incorporation into cosmetics is a growing trend.
Cecilia Dauber, Emma Parente, María Pía Zucca, Adriana Gámbaro, Ignacio Vieitez   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Defining Carers [PDF]

, 2015
The purpose of this paper is less to answer questions than to ask them, and less to define ‘carers’ than to understand who they are. In particular, its purpose is to ask why the label ‘family carer’ may be rejected by some of them, or by particular ...
Care Alliance Ireland
core   +1 more source

Enhanced chlorhexidine skin penetration with eucalyptus oil [PDF]

, 2010
Background Chlorhexidine digluconate (CHG) is a widely used skin antiseptic, however it poorly penetrates the skin, limiting its efficacy against microorganisms residing beneath the surface layers of skin. The aim of the current study was to improve the
Conway, Barbara R, Anthony C Hilton, Elliott Tom SJ, Lambert Peter A, Hilton, Anthony C, Karpanen Tarja J, Peter A Lambert, Tarja J Karpanen, Hilton Anthony C, Tony Worthington, Worthington, Tony, Karpanen, Tarja J., Elliott, T.S.J., Lambert, P.A., Karpanen, Tarja J, Worthington, T., Tom SJ Elliott, Hilton, A.C., Elliott, Tom S J, Conway Barbara R, Hilton, Anthony C., Worthington Tony, Conway, Barbara R., Karpanen, T.J., Lambert, Peter A, Lambert, Peter A., Barbara R Conway   +26 more
core   +2 more sources

A Case of Pityriasis Lichenoides Chronica Successfully Treated With Upadacitinib

Case Reports in Dermatological Medicine
Pityriasis lichenoides chronica (PLC) is a chronic cutaneous disorder of unknown cause that is thought to be a proliferation of T-cells in response to an antigen or infection. We introduce a case of a 62-year-old female who presented with an erythematous
Olivia R. Noble, David J. Cohen, Lynn Cooper   +2 more
doaj   +1 more source

Gardeniae Fructus Enhances Skin Barrier Function via AHR-Mediated FLG/LOR/IVL Expression

Molecules
Gardeniae Fructus (GF), a traditional Chinese medicine rich in iridoids, has demonstrated skin-improving effects. However, its mechanisms for enhancing epidermal barrier function remain unclear.
Kaile Zong, Fangni Zhou, Kewei Xu, Junzi Dong, Qing Huang, Jianxin Wu   +5 more
doaj   +1 more source

Improvement of Human Epidermal Barrier Structure and Lipid Profile in Xerotic- and Atopic-Prone Skin via Application of a Plant-Oil and Urea Containing pH 4.5 Emulsion

Cosmetics, 2023
Epidermal barrier dysfunction can lead to xerotic skin and promote skin disorders like atopic dermatitis. Atopic skin is characterized by reduced water-retaining compounds, altered lipid composition and elevated skin pH.
Jürgen Blaak, Dorothee Dähnhardt, Stephan Bielfeldt, Christiane Theiss, Isabel Simon, Klaus-Peter Wilhelm, Stephan Dähnhardt-Pfeiffer, Peter Staib   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Integrated, multidisciplinary care for hand eczema: design of a randomized controlled trial and cost-effectiveness study [PDF]

, 2009
Background: The individual and societal burden of hand eczema is high. Literature indicates that moderate to severe hand eczema is a disease with a poor prognosis. Many patients are hampered in their daily activities, including work.
Bruynzeel, D., Boot, C.R.L., Cécile RL Boot, Boot Cécile RL, Anema Johannes R, Coenraads, Pieter J., Derk Bruynzeel, Bruynzeel, D.P., Boot, Cecile R. L., van Gils Robin F, Anema, Johannes R., Coenraads Pieter J, Willem van Mechelen, Johannes R Anema, Coenraads, P.J., Pieter J Coenraads, Bruynzeel Derk, Bruynzeel, Derk, van der Valk Pieter GM, Gils, R.F. van, Valk, P.G.M. van der, van Gils, Robin F., van der Valk, P.G.M., Robin F van Gils, van Mechelen, W., Valk, P. van der, van der Valk, Pieter G. M., Anema, J.R., Mechelen, W. van, van Mechelen, Willem, van Gils, R.F., van der Valk, P., Pieter GM van der Valk, van Mechelen Willem   +33 more
core   +5 more sources