Results 31 to 40 of about 3,836,410 (303)

Detection of gene mutation in a case of Nagashima-type palmoplantar keratoderma

Pifu-xingbing zhenliaoxue zazhi
[Objective] To report a case of Nagashima-type palmoplantar keratoderma (NPPK), identify pathogenic gene, and assist clinical diagnosis and classification of this disease. [Methods] Clinical data of the patient were collected.
CAO Yuanyuan, YUAN Zhaojun, JIN Chuanyang, WANG Tianzi, LIAO Xiaojie, LIU Hong   +5 more
doaj   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Loss-of-function mutations in Keratin 32 gene disrupt skin immune homeostasis in pityriasis rubra pilaris

Nature Communications
Pityriasis rubra pilaris (PRP) is an inflammatory papulosquamous dermatosis, characterized by hyperkeratotic follicular papules and erythematous desquamative plaques. The precise pathogenic mechanism underlying PRP remains incompletely understood. Herein,
Peidian Shi, Wenjie Chen, Xinxing Lyu, Zhenzhen Wang, Wenchao Li, Fengming Jia, Chunzhi Zheng, Tingting Liu, Chuan Wang, Yuan Zhang, Zihao Mi, Yonghu Sun, Xuechao Chen, Shengli Chen, Guizhi Zhou, Yongxia Liu, Yingjie Lin, Fuxiang Bai, Qing Sun, Monday O. Ogese, Qiang Yu, Jianjun Liu, Hong Liu, Furen Zhang   +23 more
doaj   +1 more source

Facial skin follllicular hyperkeratosis of patients with basal cell carcinoma

Vestnik Dermatologii i Venerologii, 2017
This article provides a clinical observation of paraneoplastic syndrome of a patient with basal cell carcinoma of skin. Authors present clinical features of the described for the first time, paraneoplastic retentional follicular hyperkeratosis of facial ...
M. V. Zhuchkov, Yu. S. Bychkova, M. A. Tarasova   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Multi-organ single-cell analysis reveals PLD4 as a biomarker and potential therapeutic target of blastic plasmacytoid dendritic cell neoplasm

Cancer Cell International
Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy originating from precursors of plasmacytoid dendritic cells.
Meng Wang, Xiaotong Xue, Zhenzhen Wang, Chuan Wang, Gongqi Yu, Zihao Mi, Xu Sang, Jianwen Wang, Yongxia Liu, Xuechao Chen, Shengli Chen, Guizhi Zhou, Hong Liu, Hao Chen, Yonghu Sun, Furen Zhang   +15 more
doaj   +1 more source

Botulinum toxin injections as an effective treatment for patients with intertriginous Hailey-Hailey or Darier disease: an open-label 6-month pilot interventional study

Orphanet Journal of Rare Diseases, 2021
Background Patients with Hailey-Hailey and Darier diseases present with disabling inflammatory lesions located in large skin folds, which are often exacerbated or induced by sweating.
Isabelle Dreyfus, Aude Maza, Lauriane Rodriguez, Margot Merlos, Hélène Texier, Vanessa Rousseau, Agnès Sommet, Juliette Mazereeuw-Hautier   +7 more
doaj   +1 more source

DISEASES OF THE SKIN

The American Journal of the Medical Sciences, 1915
Printed in Great Britain. ; Includes bibliographical references. ; Mode of access: Internet.
openaire   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Pan-European early switch/early discharge opportunities exist for hospitalised patients with methicillin-resistant Staphylococcus aureus complicated skin and soft-tissue infections [PDF]

, 2014
The objective was to document pan-European real-world treatment patterns and healthcare resource use and estimate opportunities for early switch (ES) from intravenous (IV) to oral antibiotics and early discharge (ED) in hospitalised patients with ...
Solem, C.T., Haider, S., Macahilig, C., D. Simoneau, W. Lawson, C. Macahilig, Li, J.Z., Stephens, J.M., J.Z. Li, C. Eckmann, S. Haider, R. Chambers, J.M. Stephens, Simoneau, D., Eckmann, C., D. Nathwani, Lawson, W., C.T. Solem, Nathwani, D., Chambers, R., Li, J. Z.   +20 more
core   +1 more source