Results 51 to 60 of about 13,295,690 (363)

Air pollution and skin diseases: A comprehensive evaluation of the associated mechanism.

Ecotoxicology and Environmental Safety
Air pollutants deteriorate the survival environment and endanger human health around the world. A large number of studies have confirmed that air pollution jeopardizes multiple organs, such as the cardiovascular, respiratory, and central nervous systems.
Xiaoyu Gu, Zhengrui Li, Juan Su
semanticscholar   +1 more source

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana, De Schepper, Sofie, Desmet, Eline, Lambert, Jo, Speeckaert, Reinhart, Van Gele, Mireille   +5 more
core   +2 more sources

Bioengineered Skin Intended for Skin Disease Modeling [PDF]

International Journal of Molecular Sciences, 2019
Clinical use of bioengineered skin in reconstructive surgery has been established for more than 30 years. The limitations and ethical considerations regarding the use of animal models have expanded the application of bioengineered skin in the areas of disease modeling and drug screening.
Maria Sarkiri, Stephan C. Fox, Lidy E. Fratila-Apachitei, Amir A. Zadpoor   +3 more
openaire   +5 more sources

Potential of Curcumin in the Management of Skin Diseases

International Journal of Molecular Sciences
Curcumin is a polyphenolic molecule derived from the rhizoma of Curcuma longa L. This compound has been used for centuries due to its anti-inflammatory, antioxidant, and antimicrobial properties.
Kamila Kasprzak-Drozd, Przemysław Niziński, A. Hawrył, Marek Gancarz, Dominika Hawrył, Weronika Oliwa, Magdalena Pałka, Julia Markowska, A. Oniszczuk   +8 more
semanticscholar   +1 more source

The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

Frontiers in Immunology, 2020
Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells.
Taoming Liu, Sheng Li, Shuni Ying, Shunli Tang, Yuwei Ding, Yali Li, J. Qiao, H. Fang   +7 more
semanticscholar   +1 more source

Carotenoids - Effective Radical Scavengers for Healthy and Beautiful Skin [PDF]

, 2019
Free radicals are involved in various diseases and skin aging. To reduce and prevent this risk, our body produces antioxidants that can neutralize free radicals.
Darvin, Maxim E., Elpelt, Anja, Lademann, Jürgen, Lohan, Silke B., Meinke, Martina C.   +4 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Computer-Aided Diagnosis of Skin Diseases Using Deep Neural Networks

Applied Sciences, 2020
Propensity of skin diseases to manifest in a variety of forms, lack and maldistribution of qualified dermatologists, and exigency of timely and accurate diagnosis call for automated Computer-Aided Diagnosis (CAD).
Muhammad Naseer Bajwa, Kaoru Muta, M. I. Malik, Shoaib Ahmed Siddiqui, S. Braun, B. Homey, A. Dengel, Sheraz Ahmed   +7 more
semanticscholar   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Multi-organ single-cell analysis reveals PLD4 as a biomarker and potential therapeutic target of blastic plasmacytoid dendritic cell neoplasm

Cancer Cell International
Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy originating from precursors of plasmacytoid dendritic cells.
Meng Wang, Xiaotong Xue, Zhenzhen Wang, Chuan Wang, Gongqi Yu, Zihao Mi, Xu Sang, Jianwen Wang, Yongxia Liu, Xuechao Chen, Shengli Chen, Guizhi Zhou, Hong Liu, Hao Chen, Yonghu Sun, Furen Zhang   +15 more
doaj   +1 more source