Results 51 to 60 of about 1,694,406 (363)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Penile herpes zoster: an unusual location for a common disease

open access: yesBrazilian Journal of Infectious Diseases
Herpes zoster is a common dermatological condition which affects up to 20% of the population, most frequently involving the thoracic and facial dermatomes with sacral lesions occurring rarely and only a few reported cases of penile shingles. Case report:
Milan Bjekic   +2 more
doaj   +1 more source

A new gender-specific model for skin autofluorescence risk stratification [PDF]

open access: yes, 2015
Advanced glycation endproducts (AGEs) are believed to play a significant role in the pathophysiology of a variety of diseases including diabetes and cardiovascular diseases.
Ahmad, MS   +4 more
core   +1 more source

Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports [PDF]

open access: gold, 2023
Iva Bešlić   +7 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Invited review: Camel skin diseases survey in Morocco [PDF]

open access: yes, 2019
The present study aimed to collect data related to skin diseases in dromedary camels in the south of Morocco. As a whole, 168 herds from 9 provinces located in the south of Morocco have been prospected.
Bengoumi, Mohammed   +3 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

In Silico Approaches and the Role of Ontologies in Aging Research [PDF]

open access: yes, 2013
The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means.
Busch, Hauke   +14 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Sistem Pakar Identifikasi Penyakit Kulit Anjing Menggunakan Metode Certainty Factor [PDF]

open access: yes, 2015
Dogs are common animal that found as pets in Indonesia. Indonesia as a tropical country has a high humidity, where fungi and parasites easily to multiply on animal skin. The fungi and parasites are one of the causes of dog skin diseases.
Hakim, A. M. (Arnaz)   +2 more
core  

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