Results 221 to 230 of about 938,782 (286)

Nail Toxicities Associated With Anticancer Therapies in Children

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

Scale of Alopecia Areata Distress (SAAD‐41): Initial Validation Part 2—Scoring, Preliminary Reference Values and Validity

open access: yesJEADV Clinical Practice, EarlyView.
The SAAD‐41 is a 41‐item scale developed to comprehensively assess Alopecia Areata psychosocial patient‐reported outcomes. Results support scoring the scale at the subdomain level and provisionally at the total‐score level. The total‐score can be calculated as a sum of the 41 SAAD items, with the sum referred to as the SAAD‐41‐Total.
Kristina Gorbatenko‐Roth   +5 more
wiley   +1 more source

Use of a Bacteriophage Lysin to Control Axillary Malodor

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Axillary malodor is primarily caused by bacteria, particularly Staphylococcus hominis, which metabolize apocrine secretions into volatile compounds. Traditional deodorants contain antiseptics that can disrupt the skin microbiome and cause irritation. Alternative methods of odor control are being sought but so far without success. We
Maurice A. M. van Steensel   +3 more
wiley   +1 more source

Pharmacokinetics and Safety of 1 mg Oral Minoxidil Tablets in Healthy Female Volunteers: A Phase I Randomized Crossover Clinical Trial

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Topical minoxidil is a first‐line treatment for female androgenetic alopecia (FAGA); however, its twice‐daily application, potential for scalp irritation and impact on hair texture can compromise adherence. Although low‐dose oral minoxidil has emerged as a promising alternative, standardized formulations with well‐characterized ...
Dolores Ochoa Mazarro   +2 more
wiley   +1 more source

Artificial Intelligence in Dermatology: Current Applications and Future Directions

open access: yesJEADV Clinical Practice, EarlyView.
This scoping review of 56 studies maps AI applications in dermatology. Image‐based classification for skin cancer detection dominates (48%), followed by clinical decision support (21%), teledermatology triage (11%), and predictive analytics (11%). While deep learning algorithms demonstrate diagnostic performance comparable to clinicians in controlled ...
Sofía Pérez‐Lalinde   +1 more
wiley   +1 more source

A Practical Guide for Incorporating Emollients in the Treatment of Mild‐to‐Moderate Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Emollients and cleansers are essential components in managing atopic dermatitis (AD). While international evidence‐based guidelines recommend using gentle cleansers and emollients daily as a foundational therapy for AD, implementation in practice remains suboptimal.
Mette Deleuran   +12 more
wiley   +1 more source

The Effects of an Educational Video on Patient Understanding of Amelanotic Melanoma

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Amelanotic melanoma (AM) is a subset of melanoma with little to no pigment that can masquerade as a benign condition, and is associated with delayed diagnosis, greater Breslow depth, higher tumour stage, and lower survival than pigmented melanoma.
Aria Wei   +3 more
wiley   +1 more source

Detergent and skin irritation

open access: yesClinics in Dermatology, 1996
U ntil the late 19th century, the only man-made surfactant was soap. Soaps are the sodium or potassium salts of fatty acids or similar products formed by the saponification or neutralization of fats or oils with organic or inorganic bases. Soaps are less useful, however, in hard water, which is high in content of multivalent ions, such as calcium and ...
Effendy, Isaak, Maibach, Howard I.
openaire   +4 more sources

Use of structural alerts to develop rules for identifying chemical substances with skin irritation or skin corrosion potential

open access: yesQSAR and Combinatorial Science, 2005
In this paper structural alerts for acute skin lesions were categorized as irritation or corrosion or a combination of corrosion/irritation alerts. Categorizing the alerts according to their mechanisms of skin irritation and corrosion and connecting them
Schlegel, K.   +7 more
exaly   +2 more sources
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The modulation of skin irritation

Contact Dermatitis, 1994
Irritant contact dermatitis (ICD) is a multifactorial disease, the onset and modulation of which depend on both endogenous and exogenous factors. Among the former, age, race, site, sex and history of dermatitis may all be important. Such variables can now readily be quantified by objective noninvasive techniques, such as measurement of transepidermal ...
E, Berardesca, F, Distante
openaire   +2 more sources

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