Results 41 to 50 of about 326,460 (261)

Feature Learning and Boundary Guidance for Skin Lesion Image Segmentation Network [PDF]

open access: yesJisuanji gongcheng
Skin lesion images significantly affect the accuracy of segmentation algorithms because of characteristics such as blurred lesion boundaries, large variations in size, and irregular shapes.
LIU Menghan, LIU Li, FU Xiaodong, LIU Lijun, PENG Wei
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Clinical characteristics associated with Borrelia burgdorferi sensu lato skin culture results in patients with erythema migrans. [PDF]

open access: yesPLoS ONE, 2013
Clinical characteristics associated with isolation of Borrelia burgdorferi sensu lato from skin have not been fully evaluated. To gain insight into predictors for a positive EM skin culture, we compared basic demographic, epidemiologic, and clinical data
Franc Strle   +9 more
doaj   +1 more source

Registration of dermatoscopic images of skin neoplasms and detection of structural differences

open access: yesСистемный анализ и прикладная информатика, 2023
The paper considers the application of an algorithm based on a morphological projector for determining structural differences for comparing dermoscopic images.
A. F. Smalyuk   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Adversarial Training Based Domain Adaptation of Skin Cancer Images

open access: yesLife
Skin lesion datasets used in the research are highly imbalanced; Generative Adversarial Networks can generate synthetic skin lesion images to solve the class imbalance problem, but it can result in bias and domain shift.
Syed Qasim Gilani   +4 more
doaj   +1 more source

Simple and Accurate Border Detection Algorithm for Melanoma Computer Aided Diagnosis

open access: yesDiagnostics, 2020
The interest of the scientific community for computer aided skin lesion analysis and characterization has been increased during the last years for the growing incidence of melanoma among cancerous pathologies. The detection of melanoma in its early stage
Cataldo Guaragnella, Maria Rizzi
doaj   +1 more source

Generative adversarial network image synthesis method for skin lesion generation and classification

open access: yesJournal of Medical Signals and Sensors, 2021
Background: One of the common limitations in the treatment of cancer is in the early detection of this disease. The customary medical practice of cancer examination is a visual examination by the dermatologist followed by an invasive biopsy. Nonetheless,
Freedom Mutepfe   +3 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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