Results 41 to 50 of about 313,476 (262)

Skin lesion classification from dermoscopy images using color and shape features [PDF]

Journal of Intelligent Procedures in Electrical Technology, 2017
In this study, a new algorithm for dermoscopy image classification into two types of malignant and benign is presented. At first, one preprocessing step to remove noise and also enhance image quality is performed.
hamid reza javadi, Hossein Poorghasem
doaj  

Classification of Skin Lesions Using Weighted Majority Voting Ensemble Deep Learning

Algorithms, 2022
The conventional dermatology practice of performing noninvasive screening tests to detect skin diseases is a source of escapable diagnostic inaccuracies.
Damilola A. Okuboyejo, Oludayo O. Olugbara   +1 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Simple and Accurate Border Detection Algorithm for Melanoma Computer Aided Diagnosis

Diagnostics, 2020
The interest of the scientific community for computer aided skin lesion analysis and characterization has been increased during the last years for the growing incidence of melanoma among cancerous pathologies. The detection of melanoma in its early stage
Cataldo Guaragnella, Maria Rizzi
doaj   +1 more source

Clinical characteristics associated with Borrelia burgdorferi sensu lato skin culture results in patients with erythema migrans. [PDF]

PLoS ONE, 2013
Clinical characteristics associated with isolation of Borrelia burgdorferi sensu lato from skin have not been fully evaluated. To gain insight into predictors for a positive EM skin culture, we compared basic demographic, epidemiologic, and clinical data
Franc Strle, Lara Lusa, Eva Ružić-Sabljić, Vera Maraspin, Stanka Lotrič Furlan, Jože Cimperman, Katarina Ogrinc, Tereza Rojko, Jerneja Videčnik Zorman, Daša Stupica   +9 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Adversarial Training Based Domain Adaptation of Skin Cancer Images

Life
Skin lesion datasets used in the research are highly imbalanced; Generative Adversarial Networks can generate synthetic skin lesion images to solve the class imbalance problem, but it can result in bias and domain shift.
Syed Qasim Gilani, Muhammad Umair, Maryam Naqvi, Oge Marques, Hee-Cheol Kim   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Skin Lesion Segmentation Using Image Bit-Plane Multilayer Approach

Applied Sciences, 2020
The establishment of automatic diagnostic systems able to detect and classify skin lesions at the initial stage are getting really relevant and effective in providing support for medical personnel during clinical assessment.
Maria Rizzi, Cataldo Guaragnella
doaj   +1 more source