Neoplasms of Anal Canal and Perianal Skin [PDF]
Clinics in Colon and Rectal Surgery, 2011 Tumors of the anus and perianal skin are rare. Their presentation can vary and often mimics common benign anal pathology, thereby delaying diagnosis and appropriate and timely treatment. The anatomy of this region is complex because it represents the progressive transition from the digestive system to the skin with many different co-existing types of ...
Léonard, Daniel +2 more
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Skin, Heredity and Malignant Neoplasms [PDF]
British Journal of Cancer, 1972 Cancer control is best accomplished through its early recognition. Some inherited diseases which predispose to cancer manifest skin signs whose recognition can lead to appropriate diagnostic studies, early treatment, and genetic counseling. Dr. Lynch, through his orientation in preventive medicine and medical genetics, seeks in this book to educate the
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TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]
, 2015 Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David +8 more
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Intranasal melanoma treated with radiation therapy in three dogs [PDF]
, 2017 Three dogs were investigated for chronic unilateral nasal discharge. In all cases CT imaging showed an intranasal mass causing turbinate lysis and no evidence of metastasis.
Blackwood, L +6 more
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Metallopanstimulin as a marker for head and neck cancer [PDF]
, 2004 BACKGROUND: Metallopanstimulin (MPS-1) is a ribosomal protein that is found in elevated amounts in the sera of patients with head and neck squamous cell carcinoma (HNSCC).
A Agrawal +28 more
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Optimisation and validation of a PCR for Antigen Receptor Rearrangement (PARR) assay to detect clonality in canine lymphoid malignancies [PDF]
, 2016 PCR for antigen receptor gene rearrangements (PARR) analysis is being increasingly used to assist diagnosis of canine lymphoma. In this study, PARR was carried out on consecutive samples received as part of routine diagnostic practice from 271 patients ...
Gallagher, Alice +6 more
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Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. [PDF]
, 2009 BRAF and NRAS are common targets for somatic mutations in benign and malignant neoplasms that arise from melanocytes situated in epithelial structures, and lead to constitutive activation of the mitogen-activated protein (MAP) kinase pathway.
Barsh, Gregory S +8 more
core
A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors (DART SWOG 1609) in Patients with Nonpancreatic Neuroendocrine Tumors. [PDF]
, 2020 PurposeImmune checkpoint blockade has improved outcomes across tumor types; little is known about the efficacy of these agents in rare tumors. We report the results of the (nonpancreatic) neuroendocrine neoplasm cohort of SWOG S1609 dual anti-CTLA-4 and ...
Baghdadi, Tareq Al +21 more
core
MUC1 positive cutaneous metastasis with transepidermal elimination from a breast carcinoma [PDF]
, 2013 Breast cancer is the most common cause of cutaneous metastases from internal malignancies. Generally, the neoplastic cells are located in the dermis or hypodermis, while a finding of transepidermal elimination on cutaneous metastases is exceptional.
Abba, Martín Carlos +5 more
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Histopathological Evaluation of Skin Neoplasms
Nepalese Medical Journal, 2018 Introduction: Skin tumor incidence has increased over the last several decades. A wide range of tumors are encountered in clinical practice. Accurate identification of skin lesions is vital in ensuring malignancies are not missed and that they are treated early to avoid morbidity and mortality.Materials and Methods: A retrospective cross sectional ...
Shiva Raj KC, Palzum Sherpa
openaire +3 more sources