Results 41 to 50 of about 350,458 (294)

Dermatoscopy in Dermato-Oncology: Current State and Perspectives

open access: yesКреативная хирургия и онкология, 2020
Visual examination of skin neoplasms remains a completely subjective method of diagnosis and requires instrumental confirmation, which is particularly relevant with malignant neoplasms.
Z. R. Khismatullina   +2 more
doaj   +1 more source

Tumor of follicular infundibulum with unique features [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Tumor of the follicular infundibulum is a rare benign cutaneous adnexal neoplasm with variable clinical presentation. In most cases the diagnosis is made with the help of histopathology, due to lack of a characteristic clinical presentation.
Natalie Haddad   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Syndrome In Question [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Brooke-Spiegler syndrome is an autosomal dominant disorder with variable penetrance and expression. It is characterized by a genetic predisposition to develop multiple adnexal neoplasias: cylindromas, trichoepitheliomas, and trichoblastomas.
Fernanda Guedes Lavorato   +4 more
doaj   +1 more source

The p16 Antagonist Gankyrin Is Overexpressed in Melanocytic Neoplasms

open access: yesJournal of Molecular Pathology, 2022
Gankyrin has a household function in essentially all cells by acting as a chaperone in the assembly of the 26S proteasome, but also functions as a tumor-promoting protein by antagonizing the tumor suppressors retinoblastoma protein, p16, and p53.
Sara Moradi, Torsten Ehrig
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Improving Skin Cancer Knowledge Among Nurse Practitioners

open access: yes, 2015
Background: The surgeon general states that skin cancer is a key public health problem. Skin cancer is highly preventable; however, it is the most commonly diagnosed cancer in the United States.|Purpose: The purpose of this scholarly project was to ...
Hartnett, Pamela D., O'Keefe, Catherine
core   +1 more source

Raman Spectroscopy in Optical Non-Invasive Diagnostics of Skin Neoplasms

open access: yesКреативная хирургия и онкология
Introduction. Recent decades indicate a significant increase in the incidence of skin cancer. Aim. To upgrade the specialized device and to improve the quality of skin neoplasm diagnostics. Materials and methods.
O. I. Kaganov   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The impact of technogenic factors on human skin cancer increase in the Odesa region

open access: yesJournal of Education, Health and Sport, 2023
It is known that malignant diseases are one of the most important medico-biological and socio-economic problems in the world and, especially, in Ukraine.
M. Lebedyuk, F. Yevchev
doaj   +1 more source

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