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Skin Pigmentation Types, Causes and Treatment—A Review [PDF]

open access: yesMolecules, 2023
Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted by genetics, UV exposure, and some drugs. Patients’ physical appearance, psychological health, and social functioning are all impacted by a sizable number of skin ...
Amin Mahmood Thawabteh   +4 more
doaj   +3 more sources

The accuracy of pulse oximetry in measuring oxygen saturation by levels of skin pigmentation: a systematic review and meta-analysis [PDF]

open access: goldBMC Medicine, 2022
Background During the COVID-19 pandemic, there have been concerns regarding potential bias in pulse oximetry measurements for people with high levels of skin pigmentation.
Chunhu Shi   +12 more
doaj   +3 more sources

Mechanism, Formulation, and Efficacy Evaluation of Natural Products for Skin Pigmentation Treatment [PDF]

open access: yesPharmaceutics
Skin pigmentation typically arises from the excessive secretion and accumulation of melanin, resulting in a darker complexion compared to normal skin. Currently, the local application of chemical drugs is a first-line strategy for pigmentation disorders,
Xueli Peng   +9 more
doaj   +3 more sources

Impact of Skin Pigmentation on Pulse Oximetry Blood Oxygenation and Wearable Pulse Rate Accuracy: Systematic Review and Meta-Analysis

open access: yesJournal of Medical Internet Research
BackgroundPhotoplethysmography (PPG) is a technology routinely used in clinical practice to assess blood oxygenation (SpO2) and pulse rate (PR). Skin pigmentation may influence accuracy, leading to health outcomes disparities.
Sanidhya Singh   +5 more
doaj   +3 more sources

Zebrafish in dermatology: a comprehensive review of their role in investigating abnormal skin pigmentation mechanisms

open access: yesFrontiers in Physiology, 2023
Skin pigmentation abnormalities, ranging from aesthetic concerns to severe hyperpigmentation disease, have profound implications for individuals’ psychological and economic wellbeing.
Junying Qu   +9 more
doaj   +2 more sources

Skin-Aging Pigmentation: Who Is the Real Enemy?

open access: yesCells, 2022
Skin aging is induced and sustained by chronological aging and photoaging. Aging skin pigmentation such as mottled pigmentation (senile lentigo) and melasma are typical signs of photoaging. The skin, like other human organs, undergoes cellular senescence,
Jin Cheol Kim   +2 more
doaj   +2 more sources

Genetic loci associated with skin pigmentation in African Americans and their effects on vitamin D deficiency.

open access: yesPLoS Genetics, 2021
A recent genome-wide association study (GWAS) in African descent populations identified novel loci associated with skin pigmentation. However, how genomic variations affect skin pigmentation and how these skin pigmentation gene variants affect serum 25 ...
Ken Batai   +11 more
doaj   +2 more sources

Melanometry for objective evaluation of skin pigmentation in pulse oximetry studies. [PDF]

open access: yesCommun Med (Lond)
Pulse oximetry enables real-time, noninvasive monitoring of arterial blood oxygen levels. However, results can vary with skin color, thus detecting disparities during clinical validation studies requires an accurate measure of skin pigmentation.
Vasudevan S   +3 more
europepmc   +2 more sources

A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

open access: greenNature Communications, 2019
We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions.
K. Adhikari   +31 more
semanticscholar   +3 more sources

Pathogenic and therapeutic role for NRF2 signaling in ultraviolet light–induced skin pigmentation

open access: yesJCI Insight, 2020
Mottled skin pigmentation and solar lentigines from chronic photodamage with aging involve complex interactions between keratinocytes and melanocytes. However, the precise signaling mechanisms that could serve as therapeutic targets are unclear.
Michelle L. Kerns   +11 more
doaj   +2 more sources

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