Results 41 to 50 of about 3,452,528 (293)
How the Skin Thickness and Thermal Contact Resistance Influence Thermal Tactile Perception
Micromachines, 2019 A few experimental studies on thermal tactile perception have shown the influence of the thermal contact resistance which relates to contact surface roughness and pressure.
Congyan Chen, Shichen Ding
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Architecture, Civil Engineering, Environment, 2023 Static pile load tests in laboratory conditions were carried out to study the mechanism of the pile skin and pile base resistance mobilization with settlement and their interactions.
Żarkiewicz Krzysztof
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Biomedicines, 2022 Many changes characterize skin aging, and the resulting dysfunctions still constitute a real challenge for our society. The aim of this study was to compare the skin aging of two rat strains, Wistar and Brown Norway (BN), considered as “poorly aging” and
Anne-France de Bengy +6 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Intestine-targeted DGAT1 inhibition improves obesity and insulin resistance without skin aberrations in mice. [PDF]
PLoS ONE, 2014 OBJECTIVE: Diacylglycerol O-acyltransferase 1 (DGAT1) catalyzes the final committed step in triglyceride biosynthesis. DGAT1 null mice are known to be resistant to diet-induced obesity, and more insulin sensitive relative to the wild-type; however, the ...
Naoto Tsuda +10 more
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Staphylococcus aureus utilizes vimentin to internalize human keratinocytes
Frontiers in Cellular and Infection MicrobiologyIntroductionVimentin is an intermediate filamentous cytoskeletal protein involved in cell migration, adhesion, and division. Recent studies have demonstrated that several bacteria and viruses interact with vimentin to facilitate entry and trafficking ...
Kyoungok Jang +5 more
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Influence of local or systemic corticosteroids on skin wound healing resistance [PDF]
Acta Cirúrgica Brasileira, 2012 PURPOSE: To compare the resistance of skin wound healing of mice submitted to local or systemic hydrocortisone administration, in different postoperative periods.
Luiz Ronaldo Alberti +2 more
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Chinese Journal of Traumatology, 2017 Purpose: Skin ulcer is a common type of disease affecting patients' health and quality of life, and bacterial infection increases the difficulty of its management.
Hang Yang +5 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source