Results 81 to 90 of about 1,109,767 (188)

Immunological characteristics of subjects with asymptomatic skin sensitization to birch and grass pollen

, 2006
Asymptomatic skin sensitization (AS) has been shown to be a risk factor for respiratory allergic ...
K. Assing, Poulsen, L K, L. K. Poulsen, Assing, Kristian, C. H. Nielsen, Nielsen, C H   +5 more
core   +1 more source

The possibility of employing cysteine and gold nanoparticles for skin sensitization analysis: current status [PDF]

, 2021
Determination of the toxicity potential of the ingredients is the first step in hazard assessment of cosmetics and personal care products. Skin sensitization analysis is one of the tests needed for the safety evaluation of these products.
Abdul Aziz, Azila, Noh, Teh Ubaidah
core  

A Perspective and a New Integrated Computational Strategy for Skin Sensitization Assessment [PDF]

, 2018
Traditionally, the skin sensitization potential of chemicals has been assessed using animal models. Due to growing ethical, political, and financial concerns, sustainable alternatives to animal testing need to be developed.
Silva, Arthur C., Hartung, Thomas, Andrade, Carolina Horta, Tropsha, Alexander, Alves, Vinicius M., Capuzzi, Stephen J., Braga, Rodolpho C., Luechtefeld, Thomas, Borba, Joyce V. B., Muratov, Eugene N.   +9 more
core   +1 more source

Use of in vitro methods combined with in silico analysis to identify potential skin sensitizers in the Tox21 10K compound library

Frontiers in Toxicology
Introduction: Skin sensitization, which leads to allergic contact dermatitis, is a key toxicological endpoint with high occupational and consumer prevalence.
Zhengxi Wei, Tuan Xu, Judy Strickland, Li Zhang, Yuhong Fang, Dingyin Tao, Anton Simeonov, Ruili Huang, Nicole C. Kleinstreuer, Menghang Xia   +9 more
doaj   +1 more source

Skin Sensitivity to Cetrimide [PDF]

Occupational and Environmental Medicine, 1949
C N D, CRUICKSHANK, J R, SQUIRE
openaire   +2 more sources

SkinSensDB: A curated database for skin sensitization assays

, 2017
[[abstract]]Skin sensitization is an important toxicological endpoint for chemical hazard determination and safety assessment. Prediction of chemical skin sensitizer had traditionally relied on data from rodent models.
Wang, CC;Lin, YC;Wang, SS;Shih, C;Lin, YH;Tung, CW
core   +1 more source

Toxicity evaluation of metsulfuron-methyl, nicosulfuron, and methoxyfenozide as pesticides in Indonesia

Open Agriculture
Pesticides are substances widely used to control or eliminate pests, including weeds, insects, and other harmful organisms. Agricultural pesticides, in particular, must meet specific safety and quality standards before being marketed.
Natawigena Wahyu Daradjat, Rifasta Muhammad Ilfadry, Susanto Agus, Wilar Gofarana, Suhandi Cecep   +4 more
doaj   +1 more source

Predictive identification of human skin sensitization thresholds

, 2005
For years, methods have been available for the predictive identification of chemicals that possess the intrinsic potential to cause skin sensitization. However, many have proven less suitable for the determination of relative sensitizing potency. In this
Jefferies, Donna, Dearman, Rebecca J., Gerberick, Frank, Basketter, David A., Clapp, Catherine, Ryan, Cindy A., Kimber, Ian, Safford, Bob   +7 more
core   +1 more source

Skin Sensitizers in Cosmetics and Skin Care Products

Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 2010
Cosmetics are defined as "articles with mild action on the human body, which are intended to be applied to the human body through rubbing, sprinkling or other methods, aiming to clean, beautify and increase the attractiveness, alter the appearance or to keep the skin or hair in good condition (The Pharmaceutical Affairs Law: Article 2)." Consequently ...
openaire   +3 more sources

Determining a point of departure for skin sensitization potency and quantitative risk assessment of fragrance ingredients using the GARDskin dose-response assay

ALTEX: Alternatives to Animal Experimentation
Potency and quantitative risk assessment are essential for determining safe concentrations for the for­mulation of potential skin sensitizers into consumer products. Several new approach methodologies (NAMs) for skin sensitization hazard assessment have
Isabelle Lee, Andy Forreryd, Mihwa Na, Isabella Schember, Maura Lavelle, Robin Gradin, Ulrika Mattson, Henrik Johansson, Shashikiran Donthamsetty, Gregory Ladics, Anne Marie Api   +10 more
doaj   +1 more source