Results 71 to 80 of about 620,129 (315)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Changes in women's facial skin color over the ovulatory cycle are not detectable by the human visual system [PDF]

, 2015
RPB is supported by an Anniversary Research Fellowship at Northumbria University. MS and JT were supported by a David Philips Research Fellowship awarded to MS by the Biological Sciences Research Council (BBSRC) (BB/G022887/1).
Quigley, R., Saxton, Tamsin, Stevens, M., Robert P. Burriss (764579), Payne, J., Anthony J C Fulford, Robert P Burriss, Jenny Payne (764582), Lovell, P., Rowland, H., Martin Stevens, Burriss, Robert, P. George Lovell (764580), Rowland, Hannah M., Burriss, R., Lovell, P George, Jenny Payne, Fulford, Anthony JC, Saxton, Tamsin K, Martin Stevens (456599), Payne, Jenny, Jolyon Troscianko (456596), Troscianko, Jolyon, Jolyon Troscianko, Fulford, Anthony, Lovell, P. George, Burriss, Robert P, Hannah M. Rowland (764584), Stevens, Martin, Quigley, Rachael, Troscianko, J., Rowland, Hannah M, Rachael Quigley (764581), Fulford, Anthony J. C., Saxton, Tamsin K., Rachael Quigley, Rowland, Hannah, Tamsin K. Saxton (764583), Anthony J. C. Fulford (241917), Fulford, A., P George Lovell, Tamsin K Saxton, Lovell, P. George; id_orcid, Saxton, T., Burriss, Robert P., Hannah M Rowland   +45 more
core   +1 more source

Skin-Adaptable, Long-Lasting Moisture, and Temperature-Tolerant Hydrogel Dressings for Accelerating Burn Wound Healing without Secondary Damage [PDF]

, 2021
Developing multifunctional wound dressings, possessing not only skin-like mechanical properties and adaptability, long-lasting moisture, and temperature tolerance that maximally mimics the human skin but also on-demand adhesion without unnecessary ...
Jianhua Zhang (6347), Anjie Dong (538512), Liandong Deng (682142), Shuangyang Li (2421853), Weiwei Wang (105069), Pingsheng Huang (1630510), Zujian Feng (7288091), Yini Huangfu (11820875), Deling Kong (1444768)   +8 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Reproducibility and robustness of motor cortical stimulation to assess muscle relaxation kinetics

Physiological Reports, 2022
Transcranial magnetic stimulation (TMS) of the motor cortex can be used during a voluntary contraction to inhibit corticospinal drive to the muscle and consequently induce involuntary muscle relaxation. Our aim was to evaluate the reproducibility and the
Joery P. Molenaar, Elianne vanZandvoort, Baziel G. vanEngelen, Nicol C. Voermans, Jonne Doorduin   +4 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Haemodynamic responses to heat stress and hypohydration in resting and exercising humans: Implications for the regulation of skeletal muscle blood flow [PDF]

, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Heat stress-induced hyperthermia and exercise-induced hypohydration are associated with marked alterations in limb and systemic haemodynamics in humans ...
Pearson, James
core  

Variations of skin thermal diffusivity on different skin regions [PDF]

Background and Objective: Skin thermal diffusivity plays a crucial role in various applications, including laser therapy and cryogenic skin cooling.This study investigates the correlation between skin thermal diffusivity and two important skin parameters,
Bajrami, Dardan, Spano, Fabrizio, Rossi, René M., Fehr, Daniel, Renggli, Timon, Kirsch, Christoph, Lindhorst-Peters, Alisa, von Schulthess, Patrick, Zubiaga, Asier, Roider, Elisabeth, Huber, Stephanie, Bonmarin, Mathias, Navarini, Alexander A.   +12 more
core   +1 more source

Anti-Icing System Performance Prediction Using POD and PSO-BP Neural Networks

Aerospace
The anti-icing system is important for ice protection and flight safety. Rapid prediction of the anti-icing system’s performance is critical to reducing the design time and increasing efficiency.
Handong Mao, Xiaodan Lin, Zhimao Li, Xiaobin Shen, Wenzhao Zhao   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source