Results 71 to 80 of about 1,232,043 (309)

Challenges of measuring body temperatures of free-ranging birds and mammals [PDF]

, 2015
The thermal physiology of most birds and mammals is characterised by considerable spatial and temporal variation in body temperature. Body temperature is, therefore, a key parameter in physiological, behavioural and ecological research.
Gallon, S., McCafferty, D.J., Nord, A.
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Skin Temperature of Acupoints in Health and Primary Dysmenorrhea Patients: A Systematic Review and Meta-Analysis

Journal of Pain Research, 2023
Xuesong Wang,1,* Guang Zuo,1,* Jun Liu,1,2 Juncha Zhang,1,2 Xuliang Shi,1,2 Xisheng Fan,1,2 Xuxin Li,1 Yuanbo Gao,1 Hao Chen,1 Cun-Zhi Liu,3 Yanfen She1,2 1School of Acupuncture-Moxibustion and Tuina, Hebei University of Chinese Medicine ...
Wang X, Zuo G, Liu J, Zhang J, Shi X, Fan X, Li X, Gao Y, Chen H, Liu CZ, She Y   +10 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Skin Temperature in Master Long-Distance Runners—Results From a Field Study at the 2018 World Master Athletics Championships

Frontiers in Sports and Active Living, 2020
Older people and athletes show impairments in thermoregulation, but this has not yet been studied during a running competition. The aim of the study was to assess (1) whether there are age-related differences in skin temperature during the last stage of ...
Bergita Ganse, Hans Degens, Hans Degens
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Early Detection of Diabetes using Thermography and Artificial Neural Networks [PDF]

, 2017
The aim of this work is to demonstrate the usefulness of the artificial intelligence tools for early detection of diseases. From the historic and simple assessment of temperature by the clinical thermometer, thermal imaging camera has opened up new ...
Abdulshahed AM, Goohe HA, Alabyad FM, Saed MA   +3 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Immediate Effect of Whole-Body Vibration on Skin Temperature and Lower-Limb Blood Flow in Older Adults with Type 2 Diabetes: Pilot Study

Applied Sciences, 2020
The purpose of this study was to evaluate the response of a single whole-body vibration (WBV) training session to peripheral skin temperature and peripheral blood flow of older adults with type 2 diabetes.
Kennedy Freitas Pereira Alves, Ana Paula de Lima Ferreira, Luana Caroline de Oliveira Parente, François Talles Medeiros Rodrigues, Thais Vitorino Marques, Gabriel Barreto Antonino, Luiz Carlos de Melo, Débora Wanderley Villela, Marcelo Renato Guerino, Wagner Souza Leite, Shirley Lima Campos, Larissa Coutinho de Lucena, Redha Taiar, Maria das Graças Rodrigues de Araújo   +13 more
doaj   +1 more source

Roughness effects in turbulent forced convection [PDF]

, 2018
We conducted direct numerical simulations (DNSs) of turbulent flow over three-dimensional sinusoidal roughness in a channel. A passive scalar is present in the flow with Prandtl number $Pr=0.7$, to study heat transfer by forced convection over this rough
Chung, D., Hutchins, N., MacDonald, M.
core   +2 more sources